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Merck
CN

178810-M

Sigma-Aldrich

四氢呋喃

≥99.0%, reagent grade, contains 250 ppm BHT as inhibitor

别名:

丁烯氧化物, 四亚甲基氧化物, 氧杂环戊烷

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About This Item

经验公式(希尔记法):
C4H8O
CAS号:
分子量:
72.11
Beilstein:
102391
EC 号:
MDL编号:
UNSPSC代码:
12191501
PubChem化学物质编号:
NACRES:
NA.21
等级:
reagent grade
方案:
≥99.0%
沸点:
65-67 °C (lit.)
蒸汽压:
114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

产品名称

四氢呋喃, reagent grade, ≥99.0%, contains 250 ppm BHT as inhibitor

等级

reagent grade

蒸汽密度

2.5 (vs air)

蒸汽压

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

方案

≥99.0%

表单

liquid

自燃温度

610 °F

包含

250 ppm BHT as inhibitor

expl. lim.

1.8-11.8 %

折射率

n20/D 1.407 (lit.)

pH值(酸碱度)

~7

沸点

65-67 °C (lit.)

mp

−108 °C (lit.)

密度

0.889 g/mL at 25 °C (lit.)

SMILES字符串

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

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一般描述

Tetrahydrofuran (THF) is a saturated cyclic ether mainly used as an organic solvent. On long term storage it forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals required for the peroxide formation. THF constitutes the key fragment of various natural products (polyether antibiotics). THF can form a double hydrate with hydrogen sulfide. Crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies. Butane-1,4-diol is formed as an intermediate during the synthesis of THF. Hot THF is useful for the dissolution of polyvinylidene chloride (PVDV).

应用

Tetrahydrofuran may be used for the dissolution of poly-ε-caprolactone (PCL) and 1,3-diaminopentane, during the preparation of poly-ε-caprolactone (PCL)-hydroxyapatite (HA) scaffolds and acrylate-terminated poly(5-amino-1-pentanol-co-1,4-butanediol diacrylate) (C32)- 1,3-diaminopentane (117) polymer, respectively.

其他说明

For information on tetrahydrofuran miscibility, please visit the following link:
Tetrahydrofuran Miscibility/Immiscibility Table

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

靶器官

Respiratory system

补充剂危害

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

1.4 °F - closed cup

闪点(°C)

-17.00 °C - closed cup

法规信息

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分析证书(COA)

Lot/Batch Number

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An experimental and modeling study of the combustion of tetrahydrofuran.
Tran LS, et al.
Combustion and Flame, 162(5), 1899-1918 (2015)
Todd J Harris et al.
Biomaterials, 31(5), 998-1006 (2009-10-24)
The use of biomaterials for gene delivery can potentially avoid many of the safety concerns with viral gene delivery. However, the efficacy of polymeric gene delivery methods is low, particularly in vivo. One significant concern is that the interior and
Haiying Yu et al.
Biomaterials, 30(4), 508-517 (2008-11-01)
Natural bone growth greatly depends on the precedent vascular network that supplies oxygen and essential nutrients and removes metabolites. Likewise, it is crucial for tissue-engineered bone to establish a vascular network that temporally precedes new bone formation, and spatially originates

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