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17849

Sigma-Aldrich

恩诺沙星

≥99.0%

别名:

恩诺沙星

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250 ML
CN¥602.37

CN¥602.37

国内现货，预计发货时间April 27, 2025详情

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250 ML
CN¥602.37

About This Item

经验公式（希尔记法）:
C19H22FN3O3
CAS号:
93106-60-6
分子量:
359.39
Beilstein:
5307824
MDL编号:
MFCD00792463
UNSPSC代码:
41116105
PubChem化学物质编号:
329751571
NACRES:
NA.21

CN¥602.37

国内现货，预计发货时间April 27, 2025详情

获取大包装报价

质量水平

200

方案

≥99.0%
99.0-101.0% (dried substance)

表单

powder or crystals

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

作用机制

DNA synthesis | interferes
enzyme | inhibits

SMILES字符串

CCN1CCN(CC1)c2cc3N(C=C(C(O)=O)C(=O)c3cc2F)C4CC4

InChI

1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)

InChI key

SPFYMRJSYKOXGV-UHFFFAOYSA-N

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此商品
489331999719999
Luperox® TBH70X, 叔丁基过氧化氢 溶液 70 wt. % in H2O

458139

Luperox® TBH70X, 叔丁基过氧化氢 溶液

叔丁基过氧化氢 溶液 ~5.5 M in decane

48933

叔丁基过氧化氢 溶液

叔丁基过氧化氢 溶液 packed in FEP bottles, ~5.5 M in decane (over molecular sieve 4Å)

19997

叔丁基过氧化氢 溶液

叔丁基过氧化氢 溶液 packed in FEP bottles, ~5.5 M in nonane (over molecular sieve 4 Å)

19999

叔丁基过氧化氢 溶液

concentration

12.25-13.31% (active oxygen), 70 wt. % in H2O, 69.0-75.0% (Na2S2O3, titration)

concentration

~5.5 M in decane

concentration

52.9-66.8% (iodometric), ~5.5 M in decane (over molecular sieve 4Å)

concentration

~5.5 M in nonane (over molecular sieve 4 Å)

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

density

0.93 g/mL at 25 °C

density

-

density

0.83 g/mL at 20 °C

density

0.82 g/mL at 20 °C

form

liquid

form

-

form

liquid

form

liquid

refractive index

n20/D 1.386

refractive index

-

refractive index

n20/D 1.403

refractive index

n20/D 1.400

bp

96.2 °C

bp

-

bp

-

bp

-

一般描述

化学结构式：氟喹诺酮类
恩诺沙星是一种具有广谱抗菌活性的兽用氟喹诺酮 (FQ) 类抗生素。FQ 药物以高亲和力螯合铁。这种螯合作用导致 Fe (II) 依赖性双加氧酶的抑制，这些双加氧酶参与调节表观遗传控制、胶原成熟和 HIF（缺氧诱导因子）降解。与 FQ 药物相关的副作用为肾毒性和肌腱病变。恩诺沙星用于水产养殖，它的使用可能会引起水环境中抗生素耐药微生物的增长。该药可能对公众健康和环境产生负面影响。[1][2][3]

应用

恩诺沙星曾用于：
  • 研究氟喹诺酮类药物对哺乳动物细胞毒性的病理机制[1]
  • 利用表面增强拉曼光谱 (SERS) 分析水产养殖中使用的非法鱼药[2]
  • 作为化学发光试剂系统中的分析物[4]

象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Danger

危险声明

H302,H317,H334

危险分类

Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type N95 (US)

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000405073
    0000395311
    0000327714
    0000317511
    0000395311

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    Yanina N Martínez et al.
    Bioresource technology, 145, 280-284 (2013-04-06)
    A keratinase isolated from Paecilomyces lilacinus (LPS #876) was tested against proteins present in the skin but the high enzyme activity was detected on collagen. Keratinase was physically immobilized onto PVA-pectin cryogels and enzyme release was 20.8±2.1%, 63.8±0.2%, 41.5±3.5% and
    Jessica M Terry et al.
    The Analyst, 136(5), 913-919 (2010-12-04)
    Constructing flow-through reactors for chemiluminescence detection by machining channels into polymer disks has enabled the exploration of new configurations and materials that can improve signal intensity beyond that attainable with the traditional coiled-tubing design. Several approaches to merge reactant solutions
    Geaneth Pertunia Mashile et al.
    Polymers, 12(5) (2020-05-16)
    The application of a magnetic mesoporous carbon/β-cyclodextrin-chitosan (MMPC/Cyc-Chit) nanocomposite for the adsorptive removal of danofloxacin (DANO), enrofloxacin (ENRO) and levofloxacin (LEVO) from aqueous and environmental samples is reported in this study. The morphology and surface characteristics of the magnetic nanocomposite
    Susanne Rath et al.
    Chemosphere, 214, 111-122 (2018-09-28)
    Brazil is one of the world's largest producers of animal protein, requiring the large-scale use of veterinary drugs. The administration of antimicrobials and antiparasitics is a common practice. However, there is a lack of information on how these drugs impact
    Sook Mei Khor et al.
    Analytical and bioanalytical chemistry, 405(11), 3889-3898 (2013-02-27)
    A displacement immunoassay involves having a labelled analogue of the analyte (the epitope) already bound to the antibody. The presence of the analyte causes a competition for antibodies, and some of the antibodies dissociates from the epitope so that it
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