所有图片(1)
About This Item
经验公式（希尔记法）:
C19H22FN3O3
CAS号:
分子量:
359.39
Beilstein:
5307824
MDL编号:
UNSPSC代码:
41116105
PubChem化学物质编号:
NACRES:
NA.21
质量水平
检测方案
≥99.0%
99.0-101.0% (dried substance)
形式
powder or crystals
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
DNA synthesis | interferes
enzyme | inhibits
SMILES字符串
CCN1CCN(CC1)c2cc3N(C=C(C(O)=O)C(=O)c3cc2F)C4CC4
InChI
1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)
InChI key
SPFYMRJSYKOXGV-UHFFFAOYSA-N
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一般描述
化学结构式：氟喹诺酮类
恩诺沙星是一种具有广谱抗菌活性的兽用氟喹诺酮 (FQ) 类抗生素。FQ 药物以高亲和力螯合铁。这种螯合作用导致 Fe (II) 依赖性双加氧酶的抑制，这些双加氧酶参与调节表观遗传控制、胶原成熟和 HIF（缺氧诱导因子）降解。与 FQ 药物相关的副作用为肾毒性和肌腱病变。恩诺沙星用于水产养殖，它的使用可能会引起水环境中抗生素耐药微生物的增长。该药可能对公众健康和环境产生负面影响。
应用
恩诺沙星曾用于：
- 研究氟喹诺酮类药物对哺乳动物细胞毒性的病理机制
- 利用表面增强拉曼光谱 (SERS) 分析水产养殖中使用的非法鱼药
- 作为化学发光试剂系统中的分析物
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
WGK
WGK 3
个人防护装备
Eyeshields, Gloves, type N95 (US)
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