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Merck
CN

16633

Supelco

阿伏苯宗 CRM

analytical standard

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别名:
丁基甲氧基二苯甲酰甲烷, 阿伏苯宗
经验公式(希尔记法):
C20H22O3
CAS号:
分子量:
310.39
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

检测方案

≥99.0% (GC)

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

81-84 °C

应用

cleaning products
cosmetics
environmental
food and beverages
personal care

格式

neat

SMILES字符串

COc1ccc(cc1)C(=O)CC(=O)c2ccc(cc2)C(C)(C)C

InChI

1S/C20H22O3/c1-20(2,3)16-9-5-14(6-10-16)18(21)13-19(22)15-7-11-17(23-4)12-8-15/h5-12H,13H2,1-4H3

InChI key

XNEFYCZVKIDDMS-UHFFFAOYSA-N

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一般描述

阿伏苯宗是一种UVA过滤。用于防晒乳液和化妆品配方。它在约340-350 nm处具有最大吸收,在紫外线照射下吸收降低,导致UVA保护作用丧失。它的光稳定性非常敏感,因为它在极性质子溶剂中稳定,而在非极性溶剂中对光不稳定。

应用

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阿伏苯宗可用作以下分析物定量的分析参考标准品:
  • 使用带有二极管阵列检测器的反相高效液相色谱(RP-HPLC-DAD)的防晒制剂。
  • 使用液相色谱-正电喷雾电离-串联质谱法(LC-ESI-MS/MS)在多反应监测模式(MRM)下分析淡水、盐水样品、大鼠血浆和皮肤层

阿伏苯宗可用于研究衍生自4-丁基-4′-甲氧基二苯甲酰甲烷(BM-DBM)的封闭二酮形式的光物理特性,光敏活性。

危险声明

预防措施声明

危险分类

Aquatic Chronic 4

WGK

WGK 2

个人防护装备

Eyeshields, Gloves


分析证书(COA)

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A sensitive LC?ESI-MS/MS method for the quantification of avobenzone in rat plasma and skin layers: Application to a topical administration study
Kim GM, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1003, 41-46 (2015)
Analytical method development for simultaneous estimation of Oxybenzone, Octocrylene, Octinoxate and Avobenzone in sunscreen by high performance liquid chromatography and its validation
Bhuva C, et al.
Pharmacophore, 3(2) (2012)
Woan-Ruoh Lee et al.
Toxicology letters, 211(2), 150-158 (2012-04-10)
While laser skin resurfacing is expected to result in reduced barrier function and increased risk of drug absorption, the extent of the increment has not yet been systematically investigated. We aimed to establish the skin permeation profiles of tetracycline and
Robert M Sayre et al.
Photochemistry and photobiology, 81(2), 452-456 (2004-11-25)
A major concern raised about photostability studies of sunscreen products is that the photodegradation of sunscreens does not readily translate into changes in product performance. This study examines the correlation between photochemical degradation of sunscreen agents and changes in protection
Tatiana Armeni et al.
Toxicology, 203(1-3), 165-178 (2004-09-15)
As an extension of our previous investigations on sunscreen ingredients, the present work was aimed at assessing the possible protective effects of a common UVA-absorbing agent, Parsol 1789 (4-tert-butyl-4'-methoxydibenzoylmethane) in contact with human keratinocytes under UVA illumination. Cell viability was

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