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Merck
CN

16633

Supelco

阿伏苯宗 CRM

analytical standard

别名:

丁基甲氧基二苯甲酰甲烷, 阿伏苯宗

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About This Item

经验公式(希尔记法):
C20H22O3
CAS号:
分子量:
310.39
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

方案

≥99.0% (GC)

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

81-84 °C

应用

cleaning products
cosmetics
environmental
food and beverages
personal care

包装形式

neat

SMILES字符串

COc1ccc(cc1)C(=O)CC(=O)c2ccc(cc2)C(C)(C)C

InChI

1S/C20H22O3/c1-20(2,3)16-9-5-14(6-10-16)18(21)13-19(22)15-7-11-17(23-4)12-8-15/h5-12H,13H2,1-4H3

InChI key

XNEFYCZVKIDDMS-UHFFFAOYSA-N

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一般描述

阿伏苯宗是一种UVA过滤。用于防晒乳液和化妆品配方。它在约340-350 nm处具有最大吸收,在紫外线照射下吸收降低,导致UVA保护作用丧失。它的光稳定性非常敏感,因为它在极性质子溶剂中稳定,而在非极性溶剂中对光不稳定。

应用

有关合适的仪器技术的更多信息,请参阅产品′的检验报告。想要获得更多支持,请联系技术服务部。
阿伏苯宗可用作以下分析物定量的分析参考标准品:
  • 使用带有二极管阵列检测器的反相高效液相色谱(RP-HPLC-DAD)的防晒制剂。
  • 使用液相色谱-正电喷雾电离-串联质谱法(LC-ESI-MS/MS)在多反应监测模式(MRM)下分析淡水、盐水样品、大鼠血浆和皮肤层

阿伏苯宗可用于研究衍生自4-丁基-4′-甲氧基二苯甲酰甲烷(BM-DBM)的封闭二酮形式的光物理特性,光敏活性。

危险声明

预防措施声明

危险分类

Aquatic Chronic 4

储存分类代码

11 - Combustible Solids

WGK

WGK 2

个人防护装备

Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A sensitive LC?ESI-MS/MS method for the quantification of avobenzone in rat plasma and skin layers: Application to a topical administration study
Kim GM, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1003, 41-46 (2015)
Analytical method development for simultaneous estimation of Oxybenzone, Octocrylene, Octinoxate and Avobenzone in sunscreen by high performance liquid chromatography and its validation
Bhuva C, et al.
Pharmacophore, 3(2) (2012)
Determination of seven commonly used organic UV filters in fresh and saline waters by liquid chromatography-tandem mass spectrometry
Bratkovics S and Sapozhnikova Y
Analytical Methods : Advancing Methods and Applications, 3(12), 2943-2950 (2011)
Jing Yang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 605-612 (2008-01-30)
The objective of the present study was to determine the effects of hydroxypropyl-beta-cyclodextrin (HPCD) complexation on the transdermal penetration and photostability of a model ultraviolet A (UVA) absorber, butyl methoxydibenzoylmethane (avobenzone), and to determine the influence of complexation on in
Virginie Lhiaubet-Vallet et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 9(4), 552-558 (2010-04-01)
In most sunscreens, the presence of two UV filters usually leads to synergistic effects regarding both the final performance and photostabilization of the active principles. However, this may also result in an accelerated decomposition if a photoreaction occurs between the

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