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16382

Supelco

Casticin

analytical standard

别名:

3′,5-Dihydroxy-3,4′,6,7-tetramethoxyflavone, 3,4′,6,7-Tetra-O-methylquercetagetin, 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one, 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxychromen-4-one, Quercetagetin 3,4′,6,7-tetramethyl ether, Vitexicarpin

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About This Item

经验公式（希尔记法）:
C19H18O8
CAS号:
479-91-4
分子量:
374.34
Beilstein:
1300392
MDL编号:
MFCD00210481
UNSPSC代码:
85151701
PubChem化学物质编号:
329751207
NACRES:
NA.24

等级

analytical standard

质量水平

100

方案

≥98.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

food and beverages

包装形式

neat

储存温度

2-8°C

SMILES字符串

COc1ccc(cc1O)C2=C(OC)C(=O)c3c(O)c(OC)c(OC)cc3O2

InChI

1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3

InChI key

PJQLSMYMOKWUJG-UHFFFAOYSA-N

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一般描述

Casticin is a flavonoid, widely used as an anti-inflammatory agent. It has anti-tumor properties and is considered to be a potent immunomodulatory and cytotoxic compound.

应用

It was may be used as reference standard to compare retention time and ion peaks in plant extracts during GC/MS analysis to quantify Casticin and artemetin.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

其他说明

This compound is commonly found in plants of the genus: achillea

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCH4910
BCCD8870
BCBZ1885
BCBV0586
BCBT9439

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Fanxiang Zeng et al.
Acta biochimica et biophysica Sinica, 44(5), 442-449 (2012-03-20)
Casticin, a polymethoxyflavone from Fructus viticis used as an anti-inflammatory agent in Chinese traditional medicine, has been reported to have anti-cancer activity. The purpose of this study was to examine the apoptotic activity of casticin on human cervical cancer cells
Dan Chen et al.
Oncology reports, 26(5), 1287-1294 (2011-07-05)
Casticin, one of the main components from Fructus Viticis, has been reported to inhibit the growth of various cancer cells, including the human cervical cancer cell line HeLa. The purpose of this study was to examine the apoptotic activity and
Yun Ling et al.
Biomedical chromatography : BMC, 26(12), 1502-1508 (2012-03-13)
Casticin (3',5-dihydroxy-3, 4',6,7-tetramethoxyflavone) has been revealed to possess various kinds of pharmacological activities, including immunomodulatory, anti-hyperprolactinemia, anti-tumor and neuroprotetective activities. In order to gain an understanding of the biotransformation of casticin in vivo, a systematic method based on liquid chromatography-electrospray
Qi YE et al.
Acta pharmacologica Sinica, 31(12), 1564-1568 (2010-11-03)
to investigate the anti-hyperprolactinemia activity of casticin, a flavonoid isolated from Vitex rotundifolia, and elucidate its molecular mechanism. hyperprolactinemia (MIHP) was induced by administration of metoclopramide dihydrochloride (50 mg/kg, tid, ip, for 10 d) in SD rats and the primary
Chiara Righeschi et al.
Cancer genomics & proteomics, 9(3), 143-151 (2012-05-18)
Natural polyphenols play an important role in tumor inhibition. We used a doxorubicin-sensitive acute T-lymphoblastic leukemia cell line (CCRF-CEM) and its multidrug-resistant subline (CEM/ADR5000) to evaluate the activity of 15 plant polyphenols isolated in our laboratory (hypericin and pseudohypericin, verbascoside
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