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Merck
CN

16237

Supelco

2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl acetate

pharmaceutical impurity standard

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别名:
Aciclovir Related Compound A (USP), Aciclovir impurity A (PhEur)
经验公式(希尔记法):
C10H13N5O4
分子量:
267.24
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:

等级

analytical standard

检测方案

≥90.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

杂质

≤10.0% HPLC impurities
≤5% related solvents
≤5% water

应用

forensics and toxicology
pharmaceutical (small molecule)

格式

neat

SMILES字符串

CC(=O)OCCOCn1cnc2C(=O)NC(N)=Nc12

InChI

1S/C10H13N5O4/c1-6(16)19-3-2-18-5-15-4-12-7-8(15)13-10(11)14-9(7)17/h4H,2-3,5H2,1H3,(H3,11,13,14,17)

InChI key

DMHAXLGAKQREIL-UHFFFAOYSA-N

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一般描述

2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl acetate (impurity A) is the acetate form of acyclovir. It can be path indicative in the synthesis of acyclovir.
2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl acetate (impurity A) is the acetate form of acyclovir. It can be path indicative in the synthesis of acyclovir.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形图

Health hazard

警示用语:

Warning

危险声明

预防措施声明

危险分类

Muta. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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A L Huidobro et al.
Journal of pharmaceutical and biomedical analysis, 37(4), 687-694 (2005-03-31)
Acyclovir, guanine, and impurity A have been baseline separated with isocratic conditions at pH=3.0 and run time under 15 min by employing a SB-CN column from Agilent (150 mm x 4.6mm and 3.5 microm). Moreover, when run time was increased

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