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Merck
CN

16033

1,2-丙二醇

meets analytical specification of Ph. Eur., BP, USP, ≥99.5%

别名:

1,2-PDO, 丙二醇

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关于此项目

线性分子式:
CH3CH(OH)CH2OH
化学文摘社编号:
分子量:
76.09
UNSPSC Code:
12352100
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-338-0
Beilstein/REAXYS Number:
1340498
MDL number:
Assay:
≥99.5%
Form:
liquid
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InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

SMILES string

CC(O)CO

vapor density

2.62 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

assay

≥99.5%

form

liquid

autoignition temp.

779 °F

quality

meets analytical specification of Ph. Eur., BP, USP

shelf life

24 mo.

expl. lim.

12.5 %

impurities

acidic reac. impurities, complies, organic volatile impurities, complies (GC), oxidizing substances, complies, reducing matter, complies, residual solvents, complies, ≤0.0005% heavy metals (as Pb), ≤0.002% free alkali (as NaOH), ≤0.003% free acid (as CH3COOH), ≤0.2% water (Karl Fischer)

ign. residue

≤0.005% (as SO4)

refractive index

n20/D 1.431-1.433, n20/D 1.432 (lit.)

Quality Level

mp

−60 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

suitability

complies for appearance of solution

functional group

hydroxyl

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General description

1,2-丙二醇是一种 1,2-烷二醇。在 Ru/C 和 Amberlyst 离子交换树脂存在下,它可以通过甘油的氢解来获得。
1,2-丙二醇是一种重要的石油化学产品,可以通过甘油的氢解制备。它主要用作生物样品的冷冻保护剂,还用作食品、化妆品和制药行业的添加剂。

Application

1,2-丙二醇可用作人类胚胎和卵母细胞(人和小鼠)保存(通过冷却至零下温度)的冷冻保护剂

Packaging

在惰性气体中装瓶

Other Notes

货号16033-4X5L将停产。请订购物理性质和规格相同的单瓶16033-5L。
货号16033-6X1L将停产。请订购物理性质和规格相同的单瓶16033-1L。
货号16303-4X2.5L-R将停产。请订购物理性质和规格相同的单瓶16303-2.5L-R。

存储类别

10 - Combustible liquids

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup

ppe

Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Aqueous phase hydrogenolysis of glycerol to 1, 2-propanediol without external hydrogen addition.
Roy D, et al.
Catalysis Today, 156(1), 31-37 (2010)
D A Gook et al.
Human reproduction (Oxford, England), 8(7), 1101-1109 (1993-07-01)
Human and mouse oocytes were cryopreserved by a slow freeze, rapid thaw method, using propanediol (PROH) as the cryoprotectant. A simulated cryopreservation was also included in the study to detect the level of damage attributable to the PROH alone. Comparison
B Lassalle et al.
Fertility and sterility, 44(5), 645-651 (1985-11-01)
Eighty-five human embryos fertilized in vitro were frozen and thawed with 1,2 propanediol as a cryoprotective agent. The effects of viability of in vitro culture duration, stage, and morphologic appearance of embryos were examined after thawing. Survival was higher for
Glycerol hydrogenolysis to 1, 2-propanediol catalyzed by a heat-resistant ion-exchange resin combined with Ru/C.
Miyazawa T, et al.
Applied Catalysis A: General, 329, 30-35 (2007)
Yusha Imtiaz et al.
Nanomaterials (Basel, Switzerland), 10(8) (2020-08-23)
Polysaccharides have been shown to have immunomodulatory properties. Modulation of the immune system plays a crucial role in physiological processes as well as in the treatment and/or prevention of autoimmune and infectious diseases. Cellulose nanocrystals (CNCs) are derived from cellulose

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