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16033

Sigma-Aldrich

1,2-丙二醇

meets analytical specification of Ph. Eur., BP, USP, ≥99.5%

别名:

1,2-PDO, 丙二醇

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About This Item

线性分子式:
CH3CH(OH)CH2OH
CAS号:
57-55-6
分子量:
76.09
Beilstein:
1340498
EC 号:
200-338-0
MDL编号:
MFCD00064272
UNSPSC代码:
12352100
PubChem化学物质编号:
57647543
NACRES:
NA.21

蒸汽密度

2.62 (vs air)

质量水平

200

蒸汽压

0.08 mmHg ( 20 °C)

方案

≥99.5%

表单

liquid

自燃温度

779 °F

质量

meets analytical specification of Ph. Eur., BP, USP

保质期

24 mo.

expl. lim.

12.5 %

杂质

acidic reac. impurities, complies
 organic volatile impurities, complies (GC)
 oxidizing substances, complies
 reducing matter, complies
 residual solvents, complies
≤0.0005% heavy metals (as Pb)
≤0.002% free alkali (as NaOH)
≤0.003% free acid (as CH3COOH)
≤0.2% water (Karl Fischer)

灼烧残渣

≤0.005% (as SO4)

折射率

n20/D 1.431-1.433
n20/D 1.432 (lit.)

沸点

187 °C (lit.)

mp

−60 °C (lit.)

密度

1.036 g/mL at 25 °C (lit.)

痕量阴离子

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

适用性

complies for appearance of solution

官能团

hydroxyl

SMILES字符串

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

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相关类别

一般描述

1,2-丙二醇是一种 1,2-烷二醇。在 Ru/C 和 Amberlyst 离子交换树脂存在下，它可以通过甘油的氢解来获得。
1,2-丙二醇是一种重要的石油化学产品，可以通过甘油的氢解制备。它主要用作生物样品的冷冻保护剂，还用作食品、化妆品和制药行业的添加剂。

应用

1,2-丙二醇可用作人类胚胎和卵母细胞（人和小鼠）保存（通过冷却至零下温度）的冷冻保护剂。

包装

在惰性气体中装瓶

其他说明

货号16033-4X5L将停产。请订购物理性质和规格相同的单瓶16033-5L。
货号16033-6X1L将停产。请订购物理性质和规格相同的单瓶16033-1L。
货号16303-4X2.5L-R将停产。请订购物理性质和规格相同的单瓶16303-2.5L-R。

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

219.2 °F - closed cup

闪点(°C)

104 °C - closed cup

个人防护装备

Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
STBK7972
STBL3654
SDBB1022
STBL1129
STBK9242

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Aqueous phase hydrogenolysis of glycerol to 1, 2-propanediol without external hydrogen addition.
Roy D, et al.
Catalysis Today, 156(1), 31-37 (2010)
D A Gook et al.
Human reproduction (Oxford, England), 8(7), 1101-1109 (1993-07-01)
Human and mouse oocytes were cryopreserved by a slow freeze, rapid thaw method, using propanediol (PROH) as the cryoprotectant. A simulated cryopreservation was also included in the study to detect the level of damage attributable to the PROH alone. Comparison
Glycerol hydrogenolysis to 1, 2-propanediol catalyzed by a heat-resistant ion-exchange resin combined with Ru/C.
Miyazawa T, et al.
Applied Catalysis A: General, 329, 30-35 (2007)
B Lassalle et al.
Fertility and sterility, 44(5), 645-651 (1985-11-01)
Eighty-five human embryos fertilized in vitro were frozen and thawed with 1,2 propanediol as a cryoprotective agent. The effects of viability of in vitro culture duration, stage, and morphologic appearance of embryos were examined after thawing. Survival was higher for
Yusha Imtiaz et al.
Nanomaterials (Basel, Switzerland), 10(8) (2020-08-23)
Polysaccharides have been shown to have immunomodulatory properties. Modulation of the immune system plays a crucial role in physiological processes as well as in the treatment and/or prevention of autoimmune and infectious diseases. Cellulose nanocrystals (CNCs) are derived from cellulose
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