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Merck
CN

16033

1,2-丙二醇

meets analytical specification of Ph. Eur., BP, USP, ≥99.5%

别名:

1,2-PDO, 丙二醇

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关于此项目

线性分子式:
CH3CH(OH)CH2OH
化学文摘社编号:
57-55-6
分子量:
76.09
UNSPSC Code:
12352100
NACRES:
NA.21
PubChem Substance ID:
57647543
EC Number:
200-338-0
Beilstein/REAXYS Number:
1340498
MDL number:
MFCD00064272

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产品名称

1,2-丙二醇, meets analytical specification of Ph. Eur., BP, USP, ≥99.5%

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

SMILES string

CC(O)CO

vapor density

2.62 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

assay

≥99.5%

form

liquid

autoignition temp.

779 °F

quality

meets analytical specification of Ph. Eur., BP, USP

shelf life

24 mo.

expl. lim.

12.5 %

impurities

acidic reac. impurities, complies
 organic volatile impurities, complies (GC)
 oxidizing substances, complies
 reducing matter, complies
 residual solvents, complies
≤0.0005% heavy metals (as Pb)
≤0.002% free alkali (as NaOH)
≤0.003% free acid (as CH3COOH)
≤0.2% water (Karl Fischer)

ign. residue

≤0.005% (as SO4)

refractive index

n20/D 1.431-1.433
n20/D 1.432 (lit.)

bp

187 °C (lit.)

mp

−60 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

suitability

complies for appearance of solution

functional group

hydroxyl

Quality Level

200

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相关类别

Application

1,2-丙二醇可用作人类胚胎和卵母细胞（人和小鼠）保存（通过冷却至零下温度）的冷冻保护剂。

General description

1,2-丙二醇是一种 1,2-烷二醇。在 Ru/C 和 Amberlyst 离子交换树脂存在下，它可以通过甘油的氢解来获得。
1,2-丙二醇是一种重要的石油化学产品，可以通过甘油的氢解制备。它主要用作生物样品的冷冻保护剂，还用作食品、化妆品和制药行业的添加剂。

Other Notes

货号16033-4X5L将停产。请订购物理性质和规格相同的单瓶16033-5L。
货号16033-6X1L将停产。请订购物理性质和规格相同的单瓶16033-1L。
货号16303-4X2.5L-R将停产。请订购物理性质和规格相同的单瓶16303-2.5L-R。

Packaging

在惰性气体中装瓶

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup

ppe

Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SDBB6925
SDBB6486
SDBB3396
SDBB2967
SDBB2966

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Aqueous phase hydrogenolysis of glycerol to 1, 2-propanediol without external hydrogen addition.
Roy D, et al.
Catalysis Today, 156(1), 31-37 (2010)
Mohammad Chand Ali et al.
Talanta, 203, 16-22 (2019-06-17)
The efficient extraction of natural products from biomass is deemed an essential area of interest using green technology in the pharmaceutical and biochemical industries. In recent years, deep eutectic solvents (DESs) have been paying broad interest as compatible, safe, and
D A Gook et al.
Human reproduction (Oxford, England), 8(7), 1101-1109 (1993-07-01)
Human and mouse oocytes were cryopreserved by a slow freeze, rapid thaw method, using propanediol (PROH) as the cryoprotectant. A simulated cryopreservation was also included in the study to detect the level of damage attributable to the PROH alone. Comparison
B Lassalle et al.
Fertility and sterility, 44(5), 645-651 (1985-11-01)
Eighty-five human embryos fertilized in vitro were frozen and thawed with 1,2 propanediol as a cryoprotective agent. The effects of viability of in vitro culture duration, stage, and morphologic appearance of embryos were examined after thawing. Survival was higher for
Glycerol hydrogenolysis to 1, 2-propanediol catalyzed by a heat-resistant ion-exchange resin combined with Ru/C.
Miyazawa T, et al.
Applied Catalysis A: General, 329, 30-35 (2007)
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