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Merck
CN

131105

Sigma-Aldrich

原黄素 盐酸盐

Dye content 95 %

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别名:
Proflavine hydrochloride, Proflavine monohydrochloride
经验公式(希尔记法):
C13H11N3 · HCl
CAS号:
分子量:
245.71
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

检测方案

94.0% (HPLC)

形式

powder

组成

Dye content, 95%

mp

270 °C (dec.) (lit.)

溶解性

H2O: 1 mg/mL, clear

λmax

456 nm

ε (消光系数)

50000 at 260 nm in methanol

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

Cl[H].Nc1ccc2cc3ccc(N)cc3nc2c1

InChI

1S/C13H11N3.ClH/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;/h1-7H,14-15H2;1H

InChI key

PBBGTVBGXBUVLT-UHFFFAOYSA-N

应用

3, 6-Diaminoacridine hydrochloride has been used for studying cation transfer at the liquid–liquid interface.
An intercalating dye.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Anna Porfireva et al.
Nanomaterials (Basel, Switzerland), 10(5) (2020-05-14)
A DNA sensor has been developed for the determination of doxorubicin by consecutive electropolymerization of an equimolar mixture of Azure B and proflavine and adsorption of native DNA from salmon sperm on a polymer film. Electrochemical investigation showed a difference
Anirban Basu et al.
Journal of biomolecular structure & dynamics, 38(6), 1590-1597 (2019-05-07)
The binding of proflavine, an acriflavine derivative, with the RNA polynucletodide polyadenylic acid-polyuridylic acid is investigated here to understand the structural and thermodynamic basis of the binding process. Such binding data are crucial for designing viable theraperutic agents. Spectroscopic studies
Anirban Basu et al.
Journal of photochemistry and photobiology. B, Biology, 165, 42-50 (2016-10-22)
Interaction of proflavine with hemoglobin (Hgb) was studied employing spectroscopy, calorimetry, and atomic force microscopy. The equilibrium constant was found to be of the order 10
Miklós Nagy et al.
Scientific reports, 9(1), 8250-8250 (2019-06-05)
Amino-isocyanoacridines (ICAAcs), as first members of their class, turned out to be a novel, multifunctional acridine orange (AO) type dye family with a number of additional favorable properties. They have enhanced solvatochromic emission range, low quantum yields (ΦF = 2.9-0.4%) in water
Membrane activity of ionisable drugs ? a task for liquid?liquid electrochemistry?
Malkia A
Electrochemical Communications, 5:6, 473-479 (2003)

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