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About This Item
线性分子式:
C16H13NO3S · NH3
CAS号:
分子量:
316.37
Beilstein:
3581235
EC 号:
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.32
等级
technical
质量水平
检测方案
≥90% (NT)
形式
powder
颜色
, Green to Dark Green and Grey to Dark Grey and Green-Grey
溶解性
NaOH: 1 N
H2O: soluble
methanol: soluble
荧光
λex 388 nm; λem 470 nm in 0.1 M Tris, 0.2 M KCl, pH 9.0, BSA
SMILES字符串
N.OS(=O)(=O)c1cccc2cccc(Nc3ccccc3)c12
InChI
1S/C16H13NO3S.H3N/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13;/h1-11,17H,(H,18,19,20);1H3
InChI key
IPBNQYLKHUNLQE-UHFFFAOYSA-N
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应用
ANS 与环糊精形成包合物。 这种模型系统可用于模拟生物识别，并且可以通过测量游离 ANS 向络合 ANS 的荧光变化来研究。 当 ANS 进入环糊精的疏水核心时，它的荧光增加。在钠选择性光纤传感器的试剂阶段使用。 试剂相还含有铜（II）聚电解质，其在不存在钠的情况下与 ANSA 结合，并淬灭荧光。 在钠存在下，ANSA 形成阳离子复合物，产生离子对，使其发荧光。ANS 通常掺入二嵌段聚合物中，并可通过局部环境的变化（即温度，pH 等）释放。ANS 通常用作荧光探针以研究表面活性剂和两亲聚合物的分子组装，因为其最大发射量的蓝移表明该探针位于极性较低的介质中。用于蛋白质研究的荧光探针，使用稳态和动态荧光测量等方法。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Zhenyu Zuo et al.
The protein journal, 31(7), 585-591 (2012-08-10)
The interactions between Urinary Trypsin Inhibitor (UTI) and 1-anilino-8-naphthalene sulfonate (ANS) were investigated by fluorescence spectra, isothermal titration calorimetry and molecular modeling. The results revealed the presence of four specific binding sites for ANS on UTI, with interactions driven mainly
Gulam Rabbani et al.
Cell biochemistry and biophysics, 62(3), 487-499 (2012-01-05)
Here, we have characterized four pH-dependent states: alkaline state, "B" (pH 9.0), native state, "N" (pH 7.4), acid-induced state, "A" (pH 2.2) and molten globule state, "MG" (pH 1.8) of Rhizopus niveus lipase (RNL) by CD, tryptophanyl fluorescence, ANS binding
Shilpi Gupta et al.
Small (Weinheim an der Bergstrasse, Germany), 9(6), 894-904 (2012-12-12)
A new class of non-ionic dendronized multiamphiphilic polymers is prepared from a biodegradable (AB)n-type diblock polymer synthesized from 2-azido-1,3-propanediol (azido glycerol) and polyethylene glycol (PEG)-600 diethylester using Novozym-435 (Candida antarctica lipase) as a biocatalyst, following a well-established biocatalytic route. These
Silvia Zorrilla et al.
Methods in molecular biology (Clifton, N.J.), 952, 237-252 (2012-10-27)
Transcription factors of the peroxisome proliferator-activated receptor (PPAR) family are ligand-activated receptors that play key roles in lipid metabolism and inflammation. The γ isoform (PPARγ) is involved in adipocyte differentiation, insulin sensitization, and vascular pathophysiology, including inflammation and atherosclerosis, for
Tsuyoshi Konuma et al.
Proteins, 81(1), 107-118 (2012-08-29)
Chemical shift perturbations (CSPs) in NMR spectra provide useful information about the interaction of a protein with its ligands. However, in a multiple-ligand-binding system, determining quantitative parameters such as a dissociation constant (K(d) ) is difficult. Here, we used a
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