08010
黄樟素
certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
别名:
4-烯丙基-1,2-亚甲基二氧基苯, 5-烯丙基-1,3-苯并二噁茂
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关于此项目
经验公式（希尔记法）:
C10H10O2
化学文摘社编号:
分子量:
162.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
202-345-4
Beilstein/REAXYS Number:
136380
MDL number:
InChI key
ZMQAAUBTXCXRIC-UHFFFAOYSA-N
InChI
1S/C10H10O2/c1-2-3-8-4-5-9-10(6-8)12-7-11-9/h2,4-6H,1,3,7H2
SMILES string
C=CCc1ccc2OCOc2c1
grade
certified reference material, TraceCERT®
vapor pressure
1 mmHg ( 63.8 °C)
product line
TraceCERT®
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
technique(s)
gas chromatography (GC): suitable
refractive index
n20/D 1.537 (lit.)
bp
232-234 °C (lit.)
mp
11.2 °C (lit.)
density
1.095 g/mL at 25 °C (lit.)
application(s)
cleaning products
cosmetics
food and beverages
personal care
format
neat
storage temp.
2-8°C
Quality Level
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General description
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
Biochem/physiol Actions
黄樟素是在黄樟根和槟榔嚼块中发现的天然基因毒性化合物。它是致肝癌物，并且黄樟素-DNA 加合物还见于槟榔消费者的口腔癌。黄樟素的代谢产物与 DNA 形成加合物，并且会诱导染色体畸变和姐妹染色单体交换。
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
黄樟油的主要成分
Legal Information
TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Irrit. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
212.0 °F - closed cup
flash_point_c
100 °C - closed cup
法规信息
监管及禁止进口产品
此项目有
Chia-Jung Lee et al.
Molecules (Basel, Switzerland), 25(19) (2020-10-11)
Acne is a common skin condition observed in adolescents. Nutmeg (Myristica fragrans Houtt) (MF) is a well-known traditional Chinese medicine; its major toxic components, safrole and myristicin, are rich in essential oils. Essential oils of MF (MFO) were extracted by
M-J Fan et al.
Human & experimental toxicology, 31(9), 898-904 (2012-04-26)
Safrole, a component of piper betle inflorescence, is a documented rodent hepatocarcinogen and inhibits bactericidal activity and the release of superoxide anion (O(2-)) by polymorphonuclear leukocytes (PMNs). In the present study, we investigated the effects of safrole on immune responses
YanChun Zhao et al.
Gene, 509(1), 85-92 (2012-08-28)
In a previous study, we found that at low concentrations, safrole oxide (SFO) could induce vascular endothelial cell (VEC) transdifferentiation into neuron-like cells; however, whether SFO could induce bone-marrow mesenchymal stem cell (BMSC) neural differentiation was unknown. Here, we found
M Jin et al.
Toxicology, 290(2-3), 312-321 (2011-10-26)
In order to investigate a medium-term animal model using reporter gene transgenic rodents in which general toxicity, genotoxicity and carcinogenicity are evaluated, F344 gpt delta rats were given a diet containing 0.1% and 0.5% (a carcinogenic dose) safrole for 13
Mario Thevis et al.
Methods in molecular biology (Clifton, N.J.), 952, 301-312 (2012-10-27)
The elucidation of metabolic pathways and the detection of emerging therapeutics potentially enhancing athletic performance are of paramount importance to doping control authorities to protect the integrity of elite sports. A new drug candidate belonging to the family of the
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