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Merck
CN

08010

Supelco

黄樟素

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

别名:

4-烯丙基-1,2-亚甲基二氧基苯, 5-烯丙基-1,3-苯并二噁茂

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About This Item

经验公式(希尔记法):
C10H10O2
CAS号:
分子量:
162.19
Beilstein:
136380
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material
TraceCERT®

质量水平

蒸汽压

1 mmHg ( 63.8 °C)

产品线

TraceCERT®

制造商/商品名称

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

技术

gas chromatography (GC): suitable

折射率

n20/D 1.537 (lit.)

沸点

232-234 °C (lit.)

mp

11.2 °C (lit.)

密度

1.095 g/mL at 25 °C (lit.)

应用

cleaning products
cosmetics
food and beverages
personal care

包装形式

neat

储存温度

2-8°C

SMILES字符串

C=CCc1ccc2OCOc2c1

InChI

1S/C10H10O2/c1-2-3-8-4-5-9-10(6-8)12-7-11-9/h2,4-6H,1,3,7H2

InChI key

ZMQAAUBTXCXRIC-UHFFFAOYSA-N

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一般描述

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

生化/生理作用

黄樟素是在黄樟根和槟榔嚼块中发现的天然基因毒性化合物。它是致肝癌物,并且黄樟素-DNA 加合物还见于槟榔消费者的口腔癌。黄樟素的代谢产物与 DNA 形成加合物,并且会诱导染色体畸变和姐妹染色单体交换。

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

其他说明

黄樟油的主要成分

法律信息

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

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象形图

Health hazardExclamation mark

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Irrit. 2

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

212.0 °F - closed cup

闪点(°C)

100 °C - closed cup

法规信息

监管及禁止进口产品

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分析证书(COA)

Lot/Batch Number

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Chia-Jung Lee et al.
Molecules (Basel, Switzerland), 25(19) (2020-10-11)
Acne is a common skin condition observed in adolescents. Nutmeg (Myristica fragrans Houtt) (MF) is a well-known traditional Chinese medicine; its major toxic components, safrole and myristicin, are rich in essential oils. Essential oils of MF (MFO) were extracted by
Le Su et al.
Toxicology letters, 217(2), 129-136 (2012-12-29)
Safrole-2',3'-oxide (SFO) is the major electrophilic metabolite of safrole (4-allyl-1, 2-methylenedioxybenzene), a natural plant constituent found in essential oils of numerous edible herbs and spices and in food containing these herbs, such as pesto sauce, cola beverages and bologna sausages.
Chun-Shu Yu et al.
Anticancer research, 32(5), 1671-1679 (2012-05-18)
Safrole, a component of Piper betle inflorescence, is a carcinogen which has been demonstrated to induce apoptosis on human oral cancer HSC-3 cells in vitro and to inhibit HSC-3 cells in xenograft tumor cells in vivo. In our previous study
Héctor Carrasco et al.
Molecules (Basel, Switzerland), 17(1), 1002-1024 (2012-01-21)
Twenty one phenylpropanoids (including eugenol and safrole) and synthetic analogues, thirteen of them new compounds, were evaluated for antifungal properties, first with non-targeted assays against a panel of human opportunistic pathogenic fungi. Some structure-activity relationships could be observed, mainly related
Li-Ching Shen et al.
Toxicology letters, 213(3), 309-315 (2012-07-24)
Safrole, a naturally occurring product derived from spices and herbs, has been shown to be associated with the development of hepatocellular carcinoma in rodents. Safrole 2',3'-oxide (SFO), an electrophilic metabolite of safrole, was shown to react with DNA bases to

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