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等级
analytical standard
质量水平
方案
≥98.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
杂质
≤1.0% water
应用
forensics and toxicology
veterinary
包装形式
neat
SMILES字符串
CC1=CC(C(C)(C)C)=CC(C)=C1CC2=NCCN2.Cl
InChI
1S/C16H24N2.ClH/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15;/h8-9H,6-7,10H2,1-5H3,(H,17,18);1H
InChI key
YGWFCQYETHJKNX-UHFFFAOYSA-N
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一般描述
Xylometazoline hydrochloride is a derivative of imidazole, and a representative of the class of α1 agonists. It is commonly used in nasal decongestants, which works on the principle of constricting the blood vessels in the mucous membranes.
应用
Xylometazoline hydrochloride may be used as a reference standard in determining the xylometazoline hydrochloride content in samples of nasal drops using high performance liquid chromatography (HPLC).
生化/生理作用
α-肾上腺素能受体激动剂；咪唑啉结合位点配体。
警示用语：
Danger
危险声明
预防措施声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Decongestant activity of a new formulation of xylometazoline nasal spray: a double-blind, randomized versus placebo and reference drugs controlled, dose-effect study.
FC and GM
Drugs Under Experimental and Clinical Research, 28(1), 27-35 (2002)
High-performance liquid chromatographic method for the assay of dexamethasone and xylometazoline in nasal drops containing methyl p-hydroxybenzoate.
Milojevic Z, et al.
Journal of Chromatography A, 949(1-2), 79-82 (2002)
Pharmaceutical Chemistry E-Book (2011)
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