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Merck
CN

06670

Sigma-Aldrich

2-溴乙胺 氢溴酸盐

purum, ≥97.0% (AT)

别名:

2-氨基乙基溴 氢溴酸盐

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About This Item

线性分子式:
BrCH2CH2NH2 · HBr
CAS号:
分子量:
204.89
Beilstein:
3607605
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

等级

purum

质量水平

方案

≥97.0% (AT)

表单

crystalline

沸点

181.3 °C/979.2 hPa

mp

170-175 °C (lit.)
170-175 °C

溶解性

water: soluble 84.02 g/L at 28 °C
soluble

密度

0.98 g/cm3 at 28.3 °C

官能团

amine
bromo

SMILES字符串

Br.NCCBr

InChI

1S/C2H6BrN.BrH/c3-1-2-4;/h1-2,4H2;1H

InChI key

WJAXXWSZNSFVNG-UHFFFAOYSA-N

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应用

2-溴乙胺氢溴酸盐(BEA-HBr)可用作反应物制备:
  • 氨基功能化离子液体,1-胺乙基-3-甲基咪唑六氟磷酸盐([2-aemim][PF6])。[2-aemim][PF6]可作为芳族醛、丙二腈、乙酰乙酸乙酯发生Knoevenagel缩合反应合成4H-吡喃衍生物的催化剂。
  • 通过环缩合反应合成2-(N-aryl-N-芳酰基)氨基-4,5-二氢噻唑衍生物的催化剂。

也可用作尼龙表面改性的烷基化剂,以获得伯/仲/叔胺基。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 3

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

142.9 °F - Pensky-Martens closed cup

闪点(°C)

61.6 °C - Pensky-Martens closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Synthesis and QSAR Studies in 2-(N-aryl-N-aroyl) amino-4, 5-dihydrothiazole Derivatives as Potential Antithrombotic Agents
Saxena AK, et al.
Bioorganic & Medicinal Chemistry, 9(8), 2025-2034 (2001)
Amino-functionalized ionic liquid as an efficient and recyclable catalyst for Knoevenagel reactions in water
Cai Y, et al.
Catalysis Letters, 109(1-2), 61-64 (2006)
Nylon surface modification. Part 1. Targeting the amide groups for selective introduction of reactive functionalities
Jia X, et al.
Polymer, 47(14), 4916-4924 (2006)
Sally A Price et al.
Toxicologic pathology, 38(3), 346-358 (2010-03-18)
Renal papillary necrosis (RPN) is a relatively common toxicity observed in preclinical drug safety testing. It is also observed in a variety of human diseases. RPN is difficult to diagnose without expensive scanning methods or histopathology. A noninvasive biomarker that
Ana Andres-Hernando et al.
Toxicological sciences : an official journal of the Society of Toxicology, 118(2), 510-520 (2010-09-09)
Chronic analgesic abuse has been shown to induce severe renal injury characterized by renal papillary necrosis (RPN), an injury detectable at late stage. While direct toxicity of the drug may exist, the molecular mechanisms underlying analgesics induction of RPN remain

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