05670
尿囊素
≥98.0% (N)
别名:
NSC 7606, 5-脲基海因, 乙醛酸二酰脲
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关于此项目
经验公式（希尔记法）:
C4H6N4O3
化学文摘社编号:
分子量:
158.12
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-592-8
Beilstein/REAXYS Number:
102364
MDL number:
产品名称
尿囊素, ≥98.0% (N)
InChI key
POJWUDADGALRAB-UHFFFAOYSA-N
InChI
1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)
SMILES string
NC(=O)NC1NC(=O)NC1=O
assay
≥98.0% (N)
form
powder
ign. residue
≤0.2%
mp
230 °C (dec.) (lit.)
functional group
amine
Quality Level
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Application
反应物用于：
抗菌剂用曼尼希碱的合成
抗肿瘤药舒洛芬类似物的合成
抗菌剂用曼尼希碱的合成
抗肿瘤药舒洛芬类似物的合成
Biochem/physiol Actions
通过尿酸途径的嘌呤代谢物。尿酸也可与自由基反应生成尿囊素，因此尿囊素可作为氧化应激反应的有效生物标记。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Sh. Joshi
Oxidation Communications, 32, 714-723 (2009)
Khairia M. Youssef, et al
Medicinal Chemistry Research, 11, 481-503 (2003)
Rufus Turner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 891-892, 85-89 (2012-03-09)
Allantoin is the major oxidation product of urate in humans and is a potential biomarker of oxidative stress. Several methods are used to measure allantoin in biological samples but they have inherent issues that can include lack of specificity and
Dora Il'yasova et al.
Clinica chimica acta; international journal of clinical chemistry, 413(19-20), 1446-1453 (2012-06-12)
Oxidative damage produced by reactive oxygen species (ROS) has been implicated in the etiology and pathology of many health conditions, including a large number of chronic diseases. Urinary biomarkers of oxidative status present a great opportunity to study redox balance
Peng Wang et al.
Journal of agricultural and food chemistry, 60(11), 2793-2798 (2012-03-01)
Despite increasing knowledge of allantoin as a phytochemical involved in rice, relatively little is known about its distribution and function in rice grains. In this study, allantoin was quantified in 15 Chinese rice grains, and its contents varied with grain
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