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Merck
CN
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文件

04885

Supelco

L-Ascorbic acid 6-stearate

analytical standard

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别名:
6-O-Stearyl-L-ascorbic acid, L-Ascorbyl 6-octadecanoate, Ascorbyl stearate
经验公式（希尔记法）:
C24H42O7
CAS号:
10605-09-1
分子量:
442.59
EC 号:
234-231-5
UNSPSC代码:
12352200
PubChem化学物质编号:
329747987
NACRES:
NA.24

等级

analytical standard

质量水平

100

检测方案

≥97.0% (HPLC)

保质期

limited shelf life, expiry date on the label

格式

neat

InChI

1S/C24H42O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(26)30-18-19(25)23-21(27)22(28)24(29)31-23/h19,23,25,28-29H,2-18H2,1H3

InChI key

NRHBEGWPKVFGRH-UHFFFAOYSA-N

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一般描述

L-Ascorbic acid 6-stearate is a lipophilic fatty acid ester of ascorbic acid.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food.

应用

L-Ascorbic acid 6-stearate (ASC-S) may be used as a standard in determining the apoptotic activity of ASC-S through the intrinsic mitochondrial pathway in HeLa cell lines, derived from cervical cancer cells. It may also be used as an analytical standard to investigate its interaction with bovine serum albumin using surface plasmon resonance (SPR).

WGK

WGK 3

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Ascorbyl stearate promotes apoptosis through intrinsic mitochondrial pathway in HeLa cancer cells
Mane DS, et al.
Anticancer Research, 36(12), 6409-6417 (2016)
P53 enhances ascorbyl stearate-induced G2/M arrest of human ovarian cancer cells
Naidu AK, et al.
Anticancer Research, 27(6B), 3927-3934 (2007)
Kinetic and thermodynamic studies of bovine serum albumin interaction with ascorbyl palmitate and ascorbyl stearate food additives using surface plasmon resonance
Fathi F, et al.
Food Chemistry, 246(6B), 228-232 (2018)

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