04635
二甲双胍 盐酸盐
pharmaceutical secondary standard; traceable to USP and PhEur
别名:
1,1-二甲双胍 盐酸盐, 盐酸二甲双胍
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线性分子式:
NH2C(=NH)NHC(=NH)N(CH3)2 · HCl
化学文摘社编号:
分子量:
165.62
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
214-230-6
MDL number:
InChI key
OETHQSJEHLVLGH-UHFFFAOYSA-N
InChI
1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
SMILES string
Cl[H].CN(C)C(=N)NC(N)=N
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. M0605000, traceable to USP 1396309
mp
223-226 °C (lit.)
application(s)
clinical testing
format
neat
storage temp.
2-8°C
Gene Information
—
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Biochem/physiol Actions
二甲双胍是一种降糖药，可以降低血糖水平，提高胰岛素敏感性。 它的代谢作用，包括抑制肝脏糖异生，至少部分是通过激活LKB1-AMPK（AMP活化蛋白激酶）通路介导的。 这一通路的激活也参与了二甲双胍在癌细胞系中的抗增殖和促凋亡作用。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
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P H Marathe et al.
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