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等级
analytical standard
质量水平
检测方案
≥80% (HPLC)
保质期
limited shelf life, expiry date on the label
应用
food and beverages
格式
neat
储存温度
2-8°C
InChI
1S/C68H50O44/c69-22-1-14(2-23(70)39(22)79)59(93)109-56-52(92)68(112-61(95)16-5-26(73)41(81)27(74)6-16)106-34-13-103-63(97)20-11-32(46(86)50(90)38(20)37-19(64(98)107-54(34)56)9-30(77)44(84)49(37)89)104-53-21(10-31(78)45(85)51(53)91)66(100)111-58-57(110-60(94)15-3-24(71)40(80)25(72)4-15)55-33(105-67(58)101)12-102-62(96)17-7-28(75)42(82)47(87)35(17)36-18(65(99)108-55)8-29(76)43(83)48(36)88/h1-11,33-34,52,54-58,67-92,101H,12-13H2
InChI key
SHYSVHSGJVNSLX-UHFFFAOYSA-N
一般描述
Oenothein B is a dimeric ellagitannin compound which is found commonly in genusOenothera.
应用
Oenothein B may be used as a reference standard for the determination of oenothein B in aqueous extracts of Epilobii angustifolli herba and Epilobium angustifolium L. by high performance thin-layer chromatography (HPTLC)-densitometry, in plant materials by HPLC combined with diode array detector (DAD) and mass spectrometry (MS) and in Eucalyptus globulus leaves by HPLC-DAD coupled to electrospray ionization (EIS) MS.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
K Miyamoto et al.
Japanese journal of cancer research : Gann, 84(1), 99-103 (1993-01-01)
The antitumor effect of oenothein B, a macrocyclic ellagitannin from Oenothera erythrosepala Bordas, on rodent tumors was studied. Oenothein B exhibited a strong antitumor activity against MM2 ascites tumors upon intraperitoneal administration to the mice before or after the tumor
A Kiss et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 13(4), 284-289 (2006-02-24)
An aqueous extract of Epilobium angustifolium and its main compound oenothein B (OeB), a dimeric macrocyclic ellagitannin, are specifically able to induce the neutral endopeptidase (NEP) in prostate cancer cells. The angiotensin-converting enzyme (ACE) is not influenced. Additionally, a weak
Barbara Hevesi Tóth et al.
Journal of pharmaceutical and biomedical analysis, 49(1), 26-31 (2008-11-18)
Epilobium species (Onagraceae) are commonly used herbal remedies in traditional, adjuvant therapy of benignus prostate hyperplasia (BPH), however the pharmacological and clinical standardization of commercially available Epilobii herba (willow-herb) remains difficult. Willow-herb products usually consist of mixtures from various species
K Aoki et al.
Biochemical and biophysical research communications, 210(2), 329-337 (1995-05-16)
Oenothein B, a macrocircular dimeric ellagitannin, was found to be a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B suppressed glucocorticoid-sensitive mouse mammary tumor virus (MMTV) transcription in 34I cells. This suppression was accompanied by inhibition of glucocorticoid-induced endogeneous
B Ducrey et al.
Planta medica, 63(2), 111-114 (1997-04-01)
Species of the genus Epilobium (Onagraceae) have been investigated for their activity against 5 alpha-reductase and aromatase, two enzymes which are involved in the aetiology of benign prostatic hyperplasia (BPH). Activity-guided fractionation has led to the identification of two macrocyclic
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