03762
2,6-二- 叔-丁基-4-甲基苯酚
tested according to Ph. Eur.
别名:
丁基羟基甲苯, 2,6-二-叔丁基对甲酚, BHT, DBPC, 丁基化羟基甲苯
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关于此项目
线性分子式:
[(CH3)3C]2C6H2(CH3)OH
化学文摘社编号:
分子量:
220.35
UNSPSC Code:
12352300
NACRES:
NA.21
PubChem Substance ID:
EC Number:
204-881-4
Beilstein/REAXYS Number:
1911640
MDL number:
产品名称
2,6-二- 叔-丁基-4-甲基苯酚, tested according to Ph. Eur.
InChI key
NLZUEZXRPGMBCV-UHFFFAOYSA-N
InChI
1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3
SMILES string
Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C
agency
tested according to Ph. Eur.
vapor density
7.6 (vs air)
vapor pressure
<0.01 mmHg ( 20 °C)
autoignition temp.
878 °F
bp
265 °C (lit.)
mp
69-73 °C (lit.)
application(s)
pharmaceutical (small molecule)
Quality Level
Gene Information
human ... CAPN1(823)
rat ... Capn1(29153), Nos1(24598)
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Application
- 液相-质谱联用定量分析三文鱼、牛奶和黄油中残留的丁基羟基甲苯和丁基羟基茴香醚。：本研究对各种食品中残留的2,6-二叔丁基-4-甲基苯酚（BHT）和丁基羟基茴香醚（BHA）进行了定量分析。本研究考察了这些抗氧化剂在鱼类、牛奶和黄油中是否存在及其浓度，说明它们广泛应用于食品保鲜（Galal et al., 2024）。
- 固体纳米分散体促进阿维菌素生物活性的关键因素研究。：研究表明，在固体纳米分散体中应用BHT，可提高广泛使用的杀虫剂阿维菌素的生物活性。研究确定了提高制剂稳定性和有效性的关键因素，建议用于农业生物技术中（Ding et al., 2024）。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
260.6 °F - open cup
flash_point_c
127 °C - open cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
I Björkhem et al.
Arteriosclerosis and thrombosis : a journal of vascular biology, 11(1), 15-22 (1991-01-01)
Rabbits fed a 1% cholesterol diet with or without the antioxidant butylated hydroxytoluene (BHT) developed typical atherosclerotic lesions. The addition of BHT gave higher levels of total cholesterol (+40%), triglycerides (+250%), low density lipoprotein (LDL), and very low density lipoprotein
Li Li et al.
Circulation, 105(7), 861-867 (2002-02-21)
Current epidemiological data suggest that dental infections affecting tooth-supporting tissues (periodontitis) can disseminate into the systemic circulation and thereby contribute to atherosclerosis progression. To test this hypothesis, we investigated the effect of repeated systemic inoculations with Porphyromonas gingivalis (Pg), a
A M Vijesh et al.
European journal of medicinal chemistry, 46(11), 5591-5597 (2011-10-05)
In the present study two new series of Hantzsch 1,4-dihydropyridine derivatives (1,4-DHPs) containing substituted pyrazole moiety (4a-f and 5a-f) were synthesized by the reaction of 3-aryl-1H-pyrazole-4-carbaldehydes with 1,3-dicarbonylcompounds (ethylacetoacetate and methylacetoacetate) and ammonium acetate. The newly synthesized compounds were characterized
Xiao-Juan Duan et al.
Journal of natural products, 70(7), 1210-1213 (2007-07-03)
Four new highly brominated and fully substituted mono- and bis-phenols, 1-(2,3,6-tribromo-4,5-dihydroxybenzyl)pyrrolidin-2-one (1), 1,2-bis(2,3,6-tribromo-4,5-dihydroxyphenyl)ethane (2), 6-(2,3,6-tribromo-4,5-dihydroxybenzyl)-2,5-dibromo-3,4-dihydroxybenzyl methyl ether (3), and 2,3,6-tribromo-4,5-dihydroxybenzyl methyl sulfone (4), were characterized from the marine red alga Symphyocladia latiuscula. In addition, five known bromophenols, bis(2,3,6-tribromo-4,5-dihydroxyphenyl)methane (5), bis(2,3,6-tribromo-4,5-dihydroxybenzyl)
Gen-ichiro Arimura et al.
Plant physiology, 146(3), 965-973 (2008-01-01)
Continuous mechanical damage initiates the rhythmic emission of volatiles in lima bean (Phaseolus lunatus) leaves; the emission resembles that induced by herbivore damage. The effect of diurnal versus nocturnal damage on the initiation of plant defense responses was investigated using
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