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Merck
CN

03439

N-乙基二异丙胺 溶液

~2 M in 1-methyl-2-pyrrolidinone, solution, suitable for peptide synthesis

别名:

N,N-二异丙基乙胺, DIPEA, Hünig 碱

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关于此项目

经验公式(希尔记法):
C8H19N
化学文摘社编号:
分子量:
129.24
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
4124745
Form:
liquid
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产品名称

N-乙基二异丙胺 溶液, suitable for peptide synthesis, ~2 M in 1-methyl-2-pyrrolidinone

form

liquid

Quality Level

concentration

~2 M in 1-methyl-2-pyrrolidinone

impurities

≤0.2% water (KFT)

refractive index

n20/D 1.454

application(s)

peptide synthesis

functional group

amine

SMILES string

CCN(C(C)C)C(C)C

InChI

1S/C8H19N/c1-6-9(7(2)3)8(4)5/h7-8H,6H2,1-5H3

InChI key

JGFZNNIVVJXRND-UHFFFAOYSA-N

General description

N-乙基二异丙胺(EDIA)与单活化的Michael受体反应,得到对称的砜。

Application

N,N-二异丙基乙胺(DIPEA),也称为Hünig′碱,是一种空间位阻胺。它常被用作多肽合成中的碱。此外,DIPEA还被用于Pd-催化的交叉偶联反应,包括Heck偶联和Sonagashira偶联反应。


signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

73.4 °F

flash_point_c

23 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

危险化学品

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Eugene F, et al.
The Journal of Organic Chemistry, 59(9), 2599-2603 (1994)
Tristan Doussineau et al.
Journal of colloid and interface science, 339(1), 266-270 (2009-08-15)
This paper describes the preparation of two-dye-doped silica nanoparticles for ratiometric pH measurements in the biologically relevant pH-range. While a rhodamine derivative is embedded in a silica core and used as the reference, a pH-sensitive naphthalimide dye is immobilized on
J-N Volle et al.
Biosensors & bioelectronics, 19(5), 457-464 (2003-11-19)
We present a silicon chip-based approach for the enhanced sensitivity detection of surface-immobilized fluorescent molecules. Green fluorescent protein (GFP) is bound to the silicon substrate by a disuccinimidyl terephtalate-aminosilane immobilization procedure. The immobilized organic layers are characterized by surface analysis



全球贸易项目编号

货号GTIN
03439-250ML04061838618597