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Merck
CN

02390

Sigma-Aldrich

1,2-乙二硫醇

≥98.0% (GC)

别名:

1,2-二巯基乙烷, 二硫代乙二醇, 二硫甘醇

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About This Item

线性分子式:
HSCH2CH2SH
CAS号:
分子量:
94.20
Beilstein:
505946
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

蒸汽密度

>1 (vs air)

质量水平

蒸汽压

4.8 mmHg ( 20 °C)

检测方案

≥98.0% (GC)

形式

liquid

折射率

n20/D 1.558 (lit.)
n20/D 1.558

bp

144-146 °C (lit.)

mp

−41 °C (lit.)

密度

1.123 g/mL at 25 °C (lit.)

SMILES字符串

SCCS

InChI

1S/C2H6S2/c3-1-2-4/h3-4H,1-2H2

InChI key

VYMPLPIFKRHAAC-UHFFFAOYSA-N

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一般描述

1,2-乙二硫醇(EDT)是一种有机硫化合物,在化学合成中用作有机基石。它也可用作金属离子的配体来制备金属络合物。

应用

1,2-乙二硫醇可用于合成:      
  • 通过与醛或酮反应合成 1,3-二硫代烷。
  • 通过与氨基酸和甲醛的环缩合反应合成二噻吩-3-烷基烷酸。
  • EDT 还可以作为固相肽合成中的清除剂,进行有效的肽树脂脱保护。

象形图

FlameSkull and crossbones

警示用语:

Danger

危险分类

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3

WGK

WGK 3

闪点(°F)

111.2 °F

闪点(°C)

44 °C

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品

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分析证书(COA)

Lot/Batch Number

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Philip Domenico et al.
Peptides, 25(12), 2047-2053 (2004-12-02)
Staphylococci are a major cause of infections associated with indwelling medical devices. Biofilm formation on these devices adds to the antibiotic resistance seen among clinical isolates. RNAIII-inhibiting peptide (RIP) is a heptapeptide that inhibits staphylococcal pathogenesis, including biofilm formation, by
C H Sissons et al.
Oral microbiology and immunology, 15(5), 317-324 (2001-01-12)
Urease synthesis in Streptococcus salivarius is induced by an acid environment, carbohydrate and a high growth rate. We now report that both cysteine and sulfide above 1 mM strongly suppress S. salivarius urease levels. Close structural relatives of cysteine (cysteamine
P Fadden et al.
Analytical biochemistry, 225(1), 81-88 (1995-02-10)
Reaction conditions were defined for the selective quantitative derivatization and fluorophore labeling of phosphoserine residues on peptides and proteins. Phosphoserine was derivatized with 1,2-ethanedithiol using a modification of the reaction conditions defined by R. C. Clark and J. Dijkstra (1967)
Majed Halwani et al.
International journal of pharmaceutics, 373(1-2), 141-146 (2009-05-12)
Recurrent pulmonary infection and inflammation are major risk factors for high morbidity and mortality in patients with cystic fibrosis (CF). As such, frequent antibiotic use and drug resistant bacterial strains are main concerns in individuals with CF. Bacterial virulence and
Eunice F S Vieira et al.
Journal of colloid and interface science, 289(1), 42-47 (2005-07-13)
The nature of interactions between metal ions Ag(I), Hg(II), Cu(II) and chitosan derivative of 1,2-ethanedithiol, QTDT, was investigated by isothermal calorimetry using the membrane breaking technique. Simultaneous determination of thermal effects, Q(int), and amount of cation that interacts, n(int), are

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