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Merck
CN
所有图片(1)

主要文件

01580590

人参皂苷Rf

primary reference standard

别名:

(3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

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1 KIT
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About This Item

经验公式(希尔记法):
C42H72O14
CAS号:
分子量:
801.01
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24

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等级

primary reference standard

保质期

limited shelf life, expiry date on the label

制造商/商品名称

HWI

应用

food and beverages

储存温度

−20°C

SMILES字符串

[H][C@]1(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]2([H])O[C@H]3C[C@]4(C)[C@]([H])(C[C@@H](O)[C@]5([H])[C@]([H])(CC[C@@]45C)[C@@](C)(O)CC\C=C(/C)C)[C@@]6(C)CC[C@H](O)C(C)(C)[C@]36[H]

InChI

1S/C42H72O14/c1-20(2)10-9-13-42(8,52)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-37-34(32(50)30(48)25(19-44)55-37)56-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36-,37+,39+,40+,41+,42-/m0/s1

InChI key

UZIOUZHBUYLDHW-XUBRWZAZSA-N

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此商品
GALSCS0760LUC1
technique(s)

microbe id | staining: suitable

technique(s)

microbe id | staining: suitable

technique(s)

flow cytometry: suitable, protein staining: suitable

technique(s)

-

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

-

usage

 kit sufficient for 100 histochemical assays

usage

 kit sufficient for 100 tests (using a 3.5 cm dish)

usage

 kit sufficient for 1000 reactions (using 96 multiwell plates),  kit sufficient for 50 reactions (in a 2 mL cuvette)

usage

 kit sufficient for 100 assays

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−70°C

一般描述

Ginsenoside is a steroid-like molecular component having gonane steroid nucleus along with different sugar moieties attached to them found in the roots of Panax ginseng.[1] Ginsenoside Rf, a variety of ginseng saponins with attached sugars moieties which inhibits the Ca2+ channels present in primary sensory neurons.[2]
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

应用

It may be used as reference standard in HPLC-MS/MS analysis of human plasma to determine Ginsenosides from herbal products containing Panax ginseng and Panax quinquefolius.[3]

其他说明

This compound is commonly found in plants of the genus: panax

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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    Noel S Quiming et al.
    Analytical and bioanalytical chemistry, 389(5), 1477-1488 (2007-09-07)
    The influences of the organic component of the mobile phase and the column temperature on the retention of ginsenosides on a poly(vinyl alcohol) (PVA) bonded stationary phase operated under hydrophilic interaction chromatographic mode were investigated. The retention of the ginsenosides
    The antimetastatic and immunomodulating activities of ginseng minor glycosides.
    A M Popov et al.
    Doklady. Biochemistry and biophysics, 380, 309-312 (2001-12-01)
    Yue Li et al.
    European journal of pharmacology, 640(1-3), 46-54 (2010-06-29)
    The herbal products baicalin, baicalein, chlorogenic acid, and ginsenoside Rf have multiple pharmacological effects and are extensively used in alternative and/or complementary therapies. The present study investigated whether baicalin, baicalein, chlorogenic acid, and ginsenoside Rf induced the expression of the
    Ruidong Ye et al.
    Biological & pharmaceutical bulletin, 31(10), 1923-1927 (2008-10-02)
    Oxidative stress-induced cell damage has been implicated in a variety of neurodegenerative disorders. In the current study, we investigated the protective role of ginsenoside Rd against the cytotoxicity induced by exposure to hydrogen peroxide (H(2)O(2)) and the underlying mechanism in
    Sunoh Kim et al.
    Biochemical and biophysical research communications, 365(3), 399-405 (2007-11-21)
    In the present study, we have examined any possible involvement of L-type Ca(2+) channels in ginseng-mediated neuroprotective actions. Exposure to a 50mM KCl (high-K) produced neuronal cell death, which was blocked by a selective L-type Ca(2+) channel blocker in cultured

    商品

    Optimize HPLC method for ginsenoside separation using a mixture, applying it to American Ginseng root, with conditions and chromatograms shown.

    In this article we present several HPTLC applications and analytical standards for ginsenosides.

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