01542
Chrysophanol
analytical standard
别名:
1,8-Dihydroxy-3-methylanthraquinone, 3-Methylchrysazin, Chrysophanic acid
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关于此项目
经验公式（希尔记法）:
C15H10O4
化学文摘社编号:
分子量:
254.24
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-572-2
Beilstein/REAXYS Number:
1252300
MDL number:
InChI
1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
SMILES string
Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
InChI key
LQGUBLBATBMXHT-UHFFFAOYSA-N
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
192-196 °C
suitability
conforms to structure for Proton NMR spectrum
application(s)
food and beverages
format
neat
storage temp.
2-8°C
Quality Level
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General description
Chrysophanol is an anthraquinone compound and occurs naturally in Chinese herb Rheum officinale. It shows antimicrobial activity, and is an active component in many crude drugs having purgative properties.
Application
It may be used as reference standard in analyzing bioactive components (hyperin, nobiletin, hesperidin, emodin, chrysophanol, resveratrol, curcumine, and physcion) in Danning tablets using HPLC-UV and HPLC-ESI-MS.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
This compound is commonly found in plants of the genus: aloe
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells.
Lu CC
Molecular Nutrition And Food Research, 54(7), 967-976 (2010)
Chrysophanol, an antimicrobial anthraquinone from the root extract of Colubrina greggii.
Garcia-Sosa, Karlina, et al.
Journal of the Mexican Chemical Society, 50.2, 76-78 (2006)
Simultaneous analysis of eight bioactive compounds in Danning tablet by HPLC-ESI-MS and HPLC-UV.
Liu R
Journal of Pharmaceutical and Biomedical Analysis, 43(3), 1007-1012 (2007)
Haiming Chen et al.
Biomedical chromatography : BMC, 27(9), 1092-1099 (2013-03-19)
Pogostone is an important constituent of Pogostemon cablin (Blanco) Benth., and possesses various known bioactivities. A rapid, simple and sensitive liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed for the analysis of pogostone in rat plasma using chrysophanol as
Yuanyuan Zhang et al.
Colloids and surfaces. B, Biointerfaces, 103, 94-98 (2012-12-04)
Acetylene black (AB) nanoparticles were readily dispersed into water in the presence of dihexadecyl hydrogen phosphate. After evaporation of water, the surface of glassy carbon electrode (GCE) was coated with AB nanoparticles as confirmed from the scanning electron microscopy measurements.
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