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Merck
CN

00990

Sigma-Aldrich

乙酰氯

puriss. p.a., ≥99.0% (T)

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别名:
Acetic acid chloride, Acetic chloride, Ethanoyl chloride
线性分子式:
CH3COCl
CAS号:
分子量:
78.50
Beilstein:
605303
EC 号:
MDL编号:
UNSPSC代码:
12352100
eCl@ss:
39050501
PubChem化学物质编号:
NACRES:
NA.21

蒸汽密度

2.7 (vs air)

质量水平

蒸汽压

11.69 psi ( 20 °C)
32.33 psi ( 55 °C)

等级

puriss. p.a.

检测方案

≥99.0% (T)

形式

liquid

自燃温度

1353 °F

expl. lim.

19 %

折射率

n20/D 1.389 (lit.)
n20/D 1.389

bp

52 °C (lit.)

mp

−112 °C (lit.)

密度

1.104 g/mL at 25 °C (lit.)

痕量阳离子

Al: ≤0.5 mg/kg
Ba: ≤0.1 mg/kg
Bi: ≤0.1 mg/kg
Ca: ≤0.5 mg/kg
Cd: ≤0.05 mg/kg
Co: ≤0.02 mg/kg
Cr: ≤0.1 mg/kg
Cu: ≤0.02 mg/kg
Fe: ≤0.5 mg/kg
K: ≤0.5 mg/kg
Li: ≤0.1 mg/kg
Mg: ≤0.1 mg/kg
Mn: ≤0.02 mg/kg
Mo: ≤0.1 mg/kg
Na: ≤0.5 mg/kg
Ni: ≤0.02 mg/kg
Pb: ≤0.1 mg/kg
Sr: ≤0.1 mg/kg
Zn: ≤0.1 mg/kg

SMILES字符串

CC(Cl)=O

InChI

1S/C2H3ClO/c1-2(3)4/h1H3

InChI key

WETWJCDKMRHUPV-UHFFFAOYSA-N

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一般描述

乙酰氯(酰氯)是用于酯化和Friedel-Crafts酰化反应的乙酰化试剂。

应用

乙酰氯可以用作:
  • 色谱-质谱联用(MS)降解聚氧乙二醇单烷基醚,测定乙氧基化程度的降解剂。
  • 用于羧酸酯化、N-boc脱保护和磷酰胺溶剂分解反应的含醇试剂。

象形图

FlameCorrosion

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

补充剂危害

WGK

WGK 1

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Faceshields, Gloves, Goggles

法规信息

危险化学品

分析证书(COA)

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Comparisons of O-acylation and Friedel-Crafts acylation of phenols and acyl chlorides and Fries rearrangement of phenyl esters in trifluoromethanesulfonic acid: Effective synthesis of optically active homotyrosines
Murashige R, et al.
Tetrahedron, 67(3), 641-649 (2011)
A rapid and simple method for the esterification of fatty acids and steroid carboxylic acids prior to gas-liquid chromatography
Lillington JM, et al.
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Sensitive and specific assessment of the hepatic graft metabolism after liver transplantation (LTX) is essential for early detection of postoperative dysfunction implying the need for consecutive therapeutic interventions. Here, we assessed circulating liver metabolites of the cholesterol pathway, amino acids
Yu-Ting Liu et al.
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In one-photon dissociation of gaseous acetyl chloride at 248 nm, time-resolved Fourier-transform infrared emission spectroscopy is used to detect the fragments of HCl, CO, and CH(2) in the presence of Ar or O(2). The high-resolution spectra of HCl and CO
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The wide range of protein concentrations found in biological matrixes presents a formidable analytical challenge in proteomics experiments. It is predicted that low-abundance proteins are the likely clinically relevant targets in disease-based proteomics analyses. To effectively analyze low-abundance proteins by

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