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Merck
CN

00370580

人参皂苷Rg1

primary reference standard

别名:

Ginsenoside A2, Ginsenoside g1, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1, (3β,6α,12β)-3,12- 二羟基二氮杂-24烯6,20二基双 - β-D吡喃葡萄糖苷

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关于此项目

经验公式(希尔记法):
C42H72O14
化学文摘社编号:
分子量:
801.01
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
EC Number:
244-989-9
MDL number:
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产品名称

人参皂苷Rg1, primary reference standard

InChI key

YURJSTAIMNSZAE-HHNZYBFYSA-N

InChI

1S/C42H72O14/c1-20(2)10-9-13-42(8,56-37-34(52)32(50)30(48)25(19-44)55-37)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36+,37-,39+,40+,41+,42-/m0/s1

SMILES string

C[C@]12[C@@](C[C@H]([C@@]3([H])[C@]2(CC[C@]3([H])[C@@](CCC=C(C)C)(C)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C)O)([H])[C@@]5([C@@](C(C)([C@H](CC5)O)C)([H])[C@H](C1)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO)C

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

shipped in

dry ice

storage temp.

−20°C

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Application

草药产品分析的标准品。

General description

由 HWI pharma services GmbH 生产并鉴定。
通过定量 NMR 测得的准确含量可参见证书。

Other Notes

这种化合物常见于以下属的植物中:人参

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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QianKun Quan et al.
PloS one, 8(3), e59155-e59155 (2013-03-23)
The present study was designed to examine the effects of ginsenoside Rg1 on expression of peroxisome proliferator-activated receptor γ (PPARγ) and insulin-degrading enzyme (IDE) in the hippocampus of rat model of Alzheimer's disease (AD) to determine how ginsenoside Rg1 (Rg1)
Wei Li et al.
Brain research bulletin, 88(5), 501-506 (2012-05-24)
Excessive accumulation of amyloid-β (Aβ) has been proposed as a pivotal event in Alzheimer's disease (AD) pathogenesis. Possible mechanisms underlying Aβ-induced neurotoxicity include inflammation and apoptosis. Here, the protective effect of ginsenoside Rg1 (GRg1) on neuronal damage was examined in
Wei Li et al.
Life sciences, 91(15-16), 809-815 (2012-09-18)
In the present study we aimed to investigate the neuroprotective effect of ginsenoside Rg1 (GRg1) on neuronal damage examined in an adopted in vitro inflammatory neurodegeneration model and the involvement of p38 MAPK signal pathway. The supernatant from Aβ(1-40)-stimulated THP-1
Jin-Kwang Kim et al.
Journal of biotechnology, 161(3), 294-301 (2012-07-07)
This study focuses on the cloning, expression, and characterization of recombinant ginsenoside hydrolyzing glycosidase from Sanguibacter keddieii in order to biotransform ginsenosides efficiently. The gene, termed bglSk, consists of 1857 bp and revealed significant homology to that of glycoside hydrolase
Xiaoduo Guan et al.
Journal of pharmaceutical and biomedical analysis, 72, 261-266 (2012-09-27)
A simple and rapid high performance liquid chromatography electrospray ionization ion-trap tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the quantitative determination of esculentoside A (EsA) in dog plasma using ginsenoside Rg1 as the internal standard (IS).

商品

In this article we present several HPTLC applications and analytical standards for ginsenosides.

Optimize HPLC method for ginsenoside separation using a mixture, applying it to American Ginseng root, with conditions and chromatograms shown.

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