等级
SAJ first grade
蒸汽密度
3 (vs air)
蒸汽压
1.5 mmHg ( 20 °C)
检测方案
≥99.5%
自燃温度
851 °F
expl. lim.
16 %
存货情况
available only in Japan
折射率
n20/D 1.436 (lit.)
bp
204-205 °C (lit.)
mp
−45 °C (lit.)
密度
1.12 g/mL at 25 °C (lit.)
SMILES字符串
O=C1CCCO1
InChI
1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
InChI key
YEJRWHAVMIAJKC-UHFFFAOYSA-N
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生化/生理作用
γ-羟基丁酸(GHB)前体。 可通过阻断多巴胺能神经元的脉冲流,抑制多巴胺释放。 γ-丁内酯预处理可用于检测自身受体诱导的多巴胺释放。
警示用语:
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
靶器官
Central nervous system
WGK
WGK 1
闪点(°F)
closed cup
闪点(°C)
closed cup
法规信息
新产品
Journal of chromatography. A, 1056(1-2), 83-90 (2004-12-15)
We have developed a rapid method that enables the simultaneous analysis of gamma-hydroxybutyrate (GHB) and its precursors, i.e. gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in urine. The method comprised a simple dilution of the urine sample, followed by liquid chromatography-tandem mass
Biochemistry, 52(13), 2359-2370 (2013-03-07)
The in vitro evolution and engineering of quorum-quenching lactonases with enhanced reactivities was achieved using a thermostable GKL enzyme as a template, yielding the E101G/R230C GKL mutant with increased catalytic activity and a broadened substrate range [Chow, J. Y., Xue
Chemical research in toxicology, 26(3), 477-485 (2013-02-28)
Cancer development has been linked to epigenetic modifications of cancer oncogenes and tumor suppressor genes; in advanced metastatic cancers, severe epigenetic modifications are present. We previously demonstrated that the progression of prostate tumors in TRAMP mice is associated with methylation
European journal of medicinal chemistry, 60, 479-489 (2013-01-29)
Glycogen synthase kinase 3β (GSK-3β) is widely recognised as a relevant player in the pathogenesis of several highly prevalent disorders such as Alzheimer's disease, mood disorders, diabetes and cancer. Therefore, this enzyme constitutes a highly attractive therapeutic target for the
Proceedings of the National Academy of Sciences of the United States of America, 110(10), 3853-3858 (2013-02-23)
The rapid reorganization of the actin cytoskeleton in response to external stimuli is an essential property of many motile eukaryotic cells. Here, we report evidence that the actin machinery of chemotactic Dictyostelium cells operates close to an oscillatory instability. When
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