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描述
C16H18N3O4SNa (Formula)
方案
95% (from N)
分子量
Mr 371.4
包装
pkg of 5 g (10835242001)
pkg of 50 g (10835269001)
制造商/商品名称
Roche
mp
208 °C (dec.) (lit.)
溶解性
soluble (Soluble in aqueous solutions)
运输
wet ice
储存温度
2-8°C
SMILES字符串
[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3)C(O)=O
InChI
1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1
InChI key
AVKUERGKIZMTKX-NJBDSQKTSA-N
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一般描述
6-[D(-)-α-氨基苯基乙酰胺基]-青霉烷酸
溶解度：可溶于水溶液
溶解度：可溶于水溶液
内容物：钠盐
应用
氨苄青霉素已被用于选择带有质粒的耐药菌落的基因克隆策略。仅用于生命科学研究。不用于诊断操作。
生化/生理作用
β-内酰胺可被β-内酰胺酶失活。因此，氨苄青霉素是与β-内酰胺酶抑制剂一起使用的。
作用机制：氨苄西林是一种半合成的青霉素和ß-内酰胺抗生素，其通过灭活位于细菌的细胞膜内表面的转肽酶从而抑制细菌细胞壁合成。
耐药性机制：ß-内酰胺酶切开氨苄青霉素的ß-内酰胺环,使其失去活性。
抗菌谱：对革兰氏阳性菌（类似于苄青霉素）和革兰氏阴性菌（类似于四环素和氯霉素）均有效。
耐药性机制：ß-内酰胺酶切开氨苄青霉素的ß-内酰胺环,使其失去活性。
抗菌谱：对革兰氏阳性菌（类似于苄青霉素）和革兰氏阴性菌（类似于四环素和氯霉素）均有效。
其他说明
仅用于生命科学研究。不可用于诊断。
法规信息
监管及禁止进口产品
Extended-spectrum β-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat.
Bradford P A.
Clinical Microbiology Reviews, 14(4), 933-951 (2001)
Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9.
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Bio-protocol, 8(6) (2018)
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Jacobs M R, et al.
Antimicrobial Agents and Chemotherapy, 29(6), 980-985 (1986)
Shan Goh et al.
BMC biotechnology, 8, 61-61 (2008-08-13)
Antibiotic resistance genes are widely used for selection of recombinant bacteria, but their use risks contributing to the spread of antibiotic resistance. In particular, the practice is inappropriate for some intrinsically resistant bacteria and in vaccine production, and costly for
John V W Becker et al.
FEMS yeast research, 4(1), 79-85 (2003-10-14)
The stilbene resveratrol is a stress metabolite produced by Vitis vinifera grapevines during fungal infection, wounding or UV radiation. Resveratrol is synthesised particularly in the skins of grape berries and only trace amounts are present in the fruit flesh. Red
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