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描述
C3H4O6PK (Formula)
PEP, monopotassium salt
质量水平
方案
97% (PEP-K)
表单
solid
分子量
Mr 168.0 (PEP)
Mr 206.1 (PEP-K)
包装
pkg of 1 g
制造商/商品名称
Roche
储存温度
2-8°C
SMILES字符串
[K+].OC(=O)C(=C)OP(O)([O-])=O
InChI
1S/C3H5O6P.K/c1-2(3(4)5)9-10(6,7)8;/h1H2,(H,4,5)(H2,6,7,8);/q;+1/p-1
InChI key
SOSDSEAIODNVPX-UHFFFAOYSA-M
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一般描述
内容物： 80%PEP（酶法）
应用
丙酮酸激酶的底物。
磷酸烯醇式丙酮酸 (PEP) 已用于：
- 谷氨酸-半胱氨酸连接酶活性
- v-ATPase 酶活性测定
- meso 激酶测定
生化/生理作用
磷酸烯醇丙酮酸 (PEP) 在代谢中起重要作用。它具有较高的磷酸基团转移潜能，在C-C，C-P 和 C-O 键形成反应中起着通用的 C3-合成子的作用。PEP 在糖酵解的最后一步充当丙酮酸激酶 (PK) 的底物。
其他说明
仅用于生命科学研究。不可用于诊断。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Synthesis of phosphoenol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes.
Garcia A, et al.
FEBS Journal, 269(13), 3226-3236 (2002)
Glutathione participates in the modulation of starvation-induced autophagy in carcinoma cells.
Desideri E
Autophagy, 8(12), 1769-1781 (2012)
Maria B Bagh et al.
Nature communications, 8, 14612-14612 (2017-03-08)
Defective lysosomal acidification contributes to virtually all lysosomal storage disorders (LSDs) and to common neurodegenerative diseases like Alzheimer's and Parkinson's. Despite its fundamental importance, the mechanism(s) underlying this defect remains unclear. The v-ATPase, a multisubunit protein complex composed of cytosolic
Improving cell-free glycoprotein synthesis by characterizing and enriching native membrane vesicles.
Jasmine M Hershewe et al.
Nature communications, 12(1), 2363-2363 (2021-04-24)
Cell-free gene expression (CFE) systems from crude cellular extracts have attracted much attention for biomanufacturing and synthetic biology. However, activating membrane-dependent functionality of cell-derived vesicles in bacterial CFE systems has been limited. Here, we address this limitation by characterizing native
Brian S Muntean et al.
Cell reports, 34(5), 108718-108718 (2021-02-04)
The G protein alpha subunit o (Gαo) is one of the most abundant proteins in the nervous system, and pathogenic mutations in its gene (GNAO1) cause movement disorder. However, the function of Gαo is ill defined mechanistically. Here, we show
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