material
polypropylene
sterility
non-sterile
feature
holdup volume 0.2 μL
manufacturer/tradename
ZipTip®
parameter
4-70 °C temperature
technique(s)
analytical sample preparation: suitable, fractionation: suitable, protein purification: suitable (concentration)
bed volume
0.6 μL
thickness
15 μm
tip I.D.
3.375 mm
tip L
31 mm
tip O.D.
5.8 mm
tip volume
10 μL
volume
10 μL
pore size
200 Å pore size
pH
1.5-13.5, 2-12(for 24 hour exposure)
capacity
5 μg binding capacity(typically; when used with saturating amounts of analyte)
shipped in
ambient
Quality Level
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Application
用于肽或小蛋白质脱盐和浓缩的样品制备移液器吸头。
它们也适用于质谱样品制备。
它们也适用于质谱样品制备。
Features and Benefits
- 单步脱盐、浓缩和纯化
- 对复杂样品分级以获得更有意义的数据
- 适用于肽、蛋白质、核酸和更多物质
- 无死体积因此实现最大的回收率
- 消除耗时的色谱操作
Other Notes
自动化兼容性:No
Legal Information
ZIPTIP is a registered trademark of Merck KGaA, Darmstadt, Germany
Chenchang Bao et al.
Journal of proteomics, 226, 103891-103891 (2020-07-07)
Lysine crotonylation (Kcr) is a recently-discovered type of post-translational modification. Although Kcr has been reported in many species, little is known about this process in crustaceans. In this study, pan anti-lysine crotonylation antibody enrichment and high-resolution liquid chromatogram-mass spectrometry analysis
Andy Awad et al.
Microorganisms, 9(6) (2021-06-03)
Candida albicans is an opportunistic pathogenic fungus responsible for high mortality rates in immunocompromised individuals. Azole drugs such as fluconazole are the first line of therapy in fungal infection treatment. However, resistance to azole treatment is on the rise. Here
Alice Capuz et al.
Frontiers in immunology, 13, 882830-882830 (2022-07-06)
Spinal cord injury (SCI) represents a major medical challenge. At present, there is still no cure to treat it efficiently and enable functional recovery below the injury site. Previously, we demonstrated that inflammation determines the fate of the physiopathology. To
Luis Ariel Espinosa et al.
Analytical and bioanalytical chemistry, 413(30), 7559-7585 (2021-11-06)
Subunit vaccines based on the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 provide one of the most promising strategies to fight the COVID-19 pandemic. The detailed characterization of the protein primary structure by mass spectrometry (MS) is mandatory
Sha Liu et al.
Journal of proteome research, 21(7), 1589-1602 (2022-06-18)
Aberrant protein N-glycosylation is a cancer hallmark, which has great potential for cancer detection. However, large-scale and in-depth analysis of N-glycosylation remains challenging because of its high heterogeneity, complexity, and low abundance. Human saliva is an attractive diagnostic body fluid
商品
Improve your mass spectra with strategies to optimize sample preparation in protein and small molecule mass spectrometry.
相关内容
ZipTip® micro-SPE pipette tips are used as a single-step desalting, concentration, and purification tool for complex samples before mass spec analyses.
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