一般描述
Purified mouse monoclonal antibody. Recognizes the ~75 kDa SMO protein.
Recognizes the ~75 kDa SMO protein in A431 cells.
This Anti-SMO Mouse mAb (1D9) is validated for use in Immunoblotting for the detection of SMO.
免疫原
Full-length, recombinant, human SMO (aa 653-787) expressed as a GST fusion protein
应用
Immunoblotting (1-5 g/ml)
警告
Toxicity: Regulatory Review (Z)
外形
In PBS, pH 7.2.
重悬
Following initial thaw, aliquot and freeze (-20°C).
分析说明
Positive Control
A431 cells
A431 cells
其他说明
Variables associated with assay conditions will dictate the proper working dilution.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Silvia Pietrobono et al.
Cell death & disease, 9(2), 142-142 (2018-02-06)
Aberrant activation of the Hedgehog (HH) signaling is a critical driver in tumorigenesis. The Smoothened (SMO) receptor is one of the major upstream transducers of the HH pathway and a target for the development of anticancer agents. The SMO inhibitor
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