跳转至内容
Merck
CN
所有图片(1)

主要文件

安全信息

ST1204

Sigma-Aldrich

Anti-PGC-1α Rabbit pAb

liquid, Calbiochem®

别名:

PGC-1α Detection Antibody, Rabbit Anti-PGC-1α

登录查看公司和协议定价


About This Item

UNSPSC代码:
12352203
NACRES:
NA.43

生物来源

rabbit

质量水平

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

liquid

不包含

preservative

种属反应性

human, mouse, rat

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
avoid repeated freeze/thaw cycles

同位素/亚型

IgG

运输

wet ice

储存温度

−70°C

靶向翻译后修饰

unmodified

基因信息

一般描述

Protein G purified rabbit polyclonal antibody. Recognizes the ~113 kDa PGC-1α protein.
Recognizes the ~113 kDa PGC-1α protein in BAT cells.
This Anti-PGC-1α Rabbit pAb is validated for use in Immunoblotting, Immunoprecipitation for the detection of PGC-1α.

免疫原

A recombinant protein consisting of amino acids 1-120 of mouse PGC-1α

应用


Immunoblotting (not recommended)
Immunoprecipitation (1-2 g/100-200 g total protein)

警告

Toxicity: Regulatory Review (Z)

外形

In 50 mM PBS

分析说明

Positive Control
Brown adipose tissue from mice exposed to cold

其他说明

Chang, J.S., et al. 2010. J. Biol. Chem. 285, 18039.
Zhang, Y., et al. 2009. J. Biol. Chem. 284, 32813.
Lai, L., et al. 2008. Genes Dev. 14, 1948.
Rodgers, J.T., et al. 2008. FEBS Lett. 582, 46.
Mazzucotelli, A., et al. 2007. Diabetes 10, 2467.
Nemoto, S., et al. 2005. J. Biol. Chem. 16, 16456.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

未找到合适的产品?  

试试我们的产品选型工具.

储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Santosh Bhat et al.
Circulation. Heart failure, 12(3), e005529-e005529 (2019-02-26)
Proper dynamics of RNA polymerase II, such as promoter recruitment and elongation, are essential for transcription. PGC-1α (peroxisome proliferator-activated receptor [PPAR]-γ coactivator-1α), also termed PPARGC1a, is a transcriptional coactivator that stimulates energy metabolism, and PGC-1α target genes are downregulated in
Kennedy C Whitley et al.
Physiological reports, 8(14), e14517-e14517 (2020-07-31)
Calcineurin is a Ca2+ -dependent serine/threonine phosphatase that dephosphorylates nuclear factor of activated T cells (NFAT), allowing for NFAT entry into the nucleus. In skeletal muscle, calcineurin signaling and NFAT activation increases the expression of proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1α)
Elizabeth A Novak et al.
Frontiers in immunology, 14, 1231700-1231700 (2023-09-25)
We have previously demonstrated that a pathologic downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1α) within the intestinal epithelium contributes to the pathogenesis of inflammatory bowel disease (IBD). However, the mechanism underlying downregulation of PGC1α expression and activity during IBD
Ryan W Baranowski et al.
iScience, 26(7), 107047-107047 (2023-06-26)
We examined the effects of ∼30 days of spaceflight on glycogen synthase kinase 3 (GSK3) content and inhibitory serine phosphorylation in murine muscle and bone samples from four separate missions (BION-M1, rodent research [RR]1, RR9, and RR18). Spaceflight reduced GSK3β content
Valerio Donato et al.
Nature cell biology, 19(4), 341-351 (2017-03-21)
Self-renewing naive mouse embryonic stem cells (mESCs) contain few mitochondria, which increase in number and volume at the onset of differentiation. KBP (encoded by Kif1bp) is an interactor of the mitochondrial-associated kinesin Kif1Bα. We found that TDH, responsible for mitochondrial

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门