推荐产品
产品名称
C28/I2 人软骨细胞系, C28/I2 Human Chondrocyte Cell Line is widely used as a model cell line for studying normal and pathological cartilage repair mechanisms related to chondrocyte biology and physiology.
生物来源
human
质量水平
技术
cell culture | mammalian: suitable
运输
ambient
一般描述
软骨细胞是关节软骨中唯一的专门细胞类型。 它们产生分泌物来支持和修复软骨基质。 成熟关节软骨中的人软骨细胞是有丝分裂后和终末分化的细胞。 由于难以从单个关节获得足够数量的原代人软骨细胞以及由于年龄和医疗条件等因素导致的供体之间的差异，对人软骨细胞的研究受到了阻碍。
C-28/I2是源自非克隆T/C-28a4细胞的克隆系，其通过逆转录病毒载体介导的猿猴病毒SV40大T抗原（Tag）表达永生化。
C-28/I2是源自非克隆T/C-28a4细胞的克隆系，其通过逆转录病毒载体介导的猿猴病毒SV40大T抗原（Tag）表达永生化。
细胞系描述
软骨细胞
应用
根据产品文件中详述的“学术使用协议”条款，本产品预期仅用于销售和销售给学术机构，以供内部学术研究使用。有关任何其他用途的信息，请联系licensing@emdmillipore.com。
质量
• 每瓶含有≥ 1X106 个活细胞。
•通过PCR检测细胞，对HPV-16、HPV-18、甲型、乙型、丙型肝炎和HIV-1 & 2型病毒呈阴性。
•细胞对支原体污染呈阴性。
•通过STR分析对每批细胞进行基因分型，以验证细胞系的唯一身份。
•通过PCR检测细胞，对HPV-16、HPV-18、甲型、乙型、丙型肝炎和HIV-1 & 2型病毒呈阴性。
•细胞对支原体污染呈阴性。
•通过STR分析对每批细胞进行基因分型，以验证细胞系的唯一身份。
储存及稳定性
储存在液氮中。在初始解冻后，细胞可以培养至少10代，而不会显著影响细胞标志物的表达和功能。
其他说明
浓度：请参考特定批次的数据表。
免责声明
仅供研究使用在法国，在用于科研目的时（包括进口和出口活动（《公共健康法》第L 1211-1条，第2节））该产品为管制品。购买者（即最终用户）需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
高风险级别生物产品-Merck
Libo Zhou et al.
ACS applied materials & interfaces, 13(43), 51321-51332 (2021-10-20)
Various biomaterial scaffolds have been developed for improving stem cell anchorage and function in tissue constructs for in vitro and in vivo uses. Growth factors are typically applied to scaffolds to mediate cell differentiation. Conventionally, growth factors are not strictly
Meng-Huang Wu et al.
International journal of molecular sciences, 20(1) (2018-12-28)
Chondrosarcoma, a heterogeneous malignant bone tumor, commonly produces cartilage matrix, which generally has no response to conventional therapies. Studies have reported that MLN4924, a NEDD8-activating enzyme inhibitor, achieves antitumor effects against numerous malignancies. In this study, the suppressive effects of
Yanting Rao et al.
Immunity, inflammation and disease, 11(10), e978-e978 (2023-10-31)
Rheumatoid arthritis (RA) is a chronic inflammation mediated by an autoimmune response. Baculoviral IAP repeat-containing 2 (BIRC2) and tumor necrosis factor receptor 1-associated death domain protein (TRADD) have been reported to be highly expressed in RA, while their specific roles
Qunli Wang et al.
Bioengineered, 12(2), 12812-12820 (2021-12-14)
Osteoarthritis (OA) is a cartilage degenerative disease commonly observed in the elderly population and significantly impacts the normal life of OA patients. It has been reported that the development of pathological cell senescence in chondrocytes is involved in the pathogenesis
Dong-Yeong Lee et al.
Antioxidants (Basel, Switzerland), 9(1) (2020-01-23)
Antioxidant enzymes are decreased in osteoarthritis (OA) patients, implying the role of oxidative stress in osteoarthritis pathogenesis. The aim of this study was to evaluate the cytoprotective effects of delphinidin, a potent antioxidant, in human chondrocytes and the underlying mechanisms.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门