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安全信息

RTHYMAG-30K

Millipore

MILLIPLEX® 大鼠甲状腺磁珠面板-内分泌多重检测

The analytes available for this multiplex kit are: TSH, T3, T4.

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UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.47

质量水平

种属反应性

rat

制造商/商品名称

Milliplex®

assay range

sensitivity: 2255 pg/mL
(T4)

sensitivity: 284 pg/mL
(T3)

sensitivity: 38 pg/mL
(TSH)

standard curve range: 41-10,000 pg/mL
(TSH & T3)

standard curve range: 823-200,00 pg/mL
(T4)

inter-assay cv: <15%
intra-assay cv: <10%

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

一般描述

三碘甲状腺原氨酸(T3)和甲状腺素(T4)的合成和释放受垂体前叶分泌的促甲状腺激素(TSH)的调节。这些甲状腺激素在调节能量平衡、碳水化合物、脂肪酸和蛋白质的代谢中起关键作用。甲状腺激素对中枢神经和骨骼系统的发育至关重要。在研究疾病模型和治疗反应时,同时监测所有三种激素可能具有重要价值。

MILLIPLEX® 大鼠甲状腺激素是一种3重试剂盒,用于同时定量血清、血浆和组织培养样品中的以下任何或所有分析物:T3(竞争性测定),T4(竞争性测定)和TSH。该试剂盒采用96孔板,包含冻干标准混合物、两个内部检测质控品,最多可测量38份样本,一式两份。

Luminex® xMAP®平台使用磁珠免疫分析格式,以实现理想的速度和灵敏度,同时定量多种分析物,从而显著提高生产力,同时节省有价值的样品量。

面板类型:内分泌

特异性

交叉反应性
面板内分析物之间没有交叉反应或交叉反应可忽略不计。

应用

  • 分析物:T3,T4,TSH
  • 注释:T3和T4是竞争性免疫测定
  • 推荐样品类型:大鼠血清、血浆、细胞/组织培养物上清液或裂解物
  • 推荐样品稀释度:每孔25 μL 1:6稀释的血清或血浆;细胞/组织培养样品可能需要在适当的对照培养基中稀释。
  • 分析运行时间:在2-8℃下过夜(16-18小时)
  • 研究类别:内分泌
  • 研究类别:代谢

特点和优势

通过在此面板中选择可用的分析物来设计多重试剂盒。

其他说明

请联系技术服务部了解稀释线性。

法律信息

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

象形图

Skull and crossbonesEnvironment

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

WGK

WGK 3

法规信息

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Giulia Di Dalmazi et al.
Journal of immunology (Baltimore, Md. : 1950), 202(5), 1350-1362 (2019-01-25)
MYMD-1 is a synthetic derivative of tobacco alkaloids, compounds that possess immunoregulatory properties and have been linked to the epidemiological observation that smoking reduces the odds of developing thyroid Abs and hypothyroidism. To assess the effect and mechanism(s) of the
Rauf Latif et al.
Frontiers in endocrinology, 12, 706101-706101 (2021-07-20)
The synergistic activation of transcription factors can lead to thyroid progenitor cell speciation. We have previously shown in vitro that mouse or human stem cells, expressing the transcription factors NKx2-1 and Pax8, can differentiate into thyroid neo-follicular structures (TFS). We
Sujie Ke et al.
JCI insight, 6(16) (2021-07-09)
Thyroid hormone receptor β (THRB) is posttranslationally modified by small ubiquitin-like modifier (SUMO). We generated a mouse model with a mutation that disrupted sumoylation at lysine 146 (K146Q) and resulted in desumoylated THRB as the predominant form in tissues. The
The prospective protective effect of selenium nanoparticles against chromium-induced oxidative and cellular damage in rat thyroid.
Hassanin, KM; Abd El-Kawi, SH; Hashem, KS
International journal of nanomedicine null
Mirjam Kowallick et al.
Frontiers in pediatrics, 9, 723928-723928 (2021-11-23)
Introduction: High oxygen concentrations have been identified as one factor contributing to the pathogenesis of the retinopathia of prematurity, chronic lung disease of the preterm infant and preterm brain injury. Preterm infants also show short- and long-term alterations of the

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