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Merck
CN

RPTMAG-86K

MILLIPLEX® 大鼠垂体磁珠面板-内分泌多重检测

Configurable Rat Pituitary 7-Plex Panel

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UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

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产品名称

MILLIPLEX® 大鼠垂体磁珠面板-内分泌多重检测, Configurable Rat Pituitary 7-Plex Panel

packaging

1 ea of

assay range

accuracy: 75%
(GH)
accuracy: 88%
(ACTH)
accuracy: 89%
(LH)
accuracy: 90%
(TSH)
sensitivity: 0.38 pg/mL
(BDNF)
sensitivity: 0.87 pg/mL
(TSH)
sensitivity: 1.95 pg/mL
(ACTH)
sensitivity: 3.28 pg/mL
(LH)
sensitivity: 4.64 pg/mL
(Prolactin)
sensitivity: 6.50 pg/mL
(GH)
sensitivity: 7.62 pg/mL
(FSH)
standard curve range: 16-50,000 pg/mL
(GH, Prolactin)
standard curve range: 3.2-10,000 pg/mL
(ACTH, BDNF, LH, TSH)
standard curve range: 32-100,000 pg/mL
(FSH)
inter-assay cv: <20%
intra-assay cv: <10%

technique(s)

multiplexing: suitable

input

tissue/cellular extract(s)
cell culture supernatant(s)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

species reactivity

rat

manufacturer/tradename

Milliplex®

Quality Level

200

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in rat serum, plasma, tissue extract, or cell culture supernatants. Analytes Included: ACTH, BDNF, FSH, GH, LH, Prolactin, TSH Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures. Label License/Sticker for Assay Product: By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:

  • Measures seven pituitary hormones in one assay
  • Suitable for serum, plasma, and tissue lysates
  • High sensitivity and specificity
  • Multiplex format reduces sample volume and time
  • Validated under strict quality standards
Benefits:

  • Enables comprehensive endocrine profiling
  • Supports research in stress, growth, and reproductive biology
  • Saves time and resources compared to single-analyte assays
  • Provides reliable data for rodent model studies

General description

ACTH, BDNF, FSH, GH, LH, Prolactin, and TSH are key pituitary hormones involved in regulating stress, growth, reproduction, and metabolism. Their measurement provides valuable insights into neuroendocrine and reproductive function in rodent models.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

法规信息

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Victoria L Nutsch et al.
Molecular and cellular endocrinology, 442, 153-164 (2016-12-23)
Studies on the role of hormones in male reproductive aging have traditionally focused on testosterone, but estradiol (E2) also plays important roles in the control of masculine physiology and behavior. Our goal was to examine the effects of E2 on
Ivraym B Barsoum et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(7), 2657-2666 (2013-04-10)
Testes contain two distinct Leydig cell populations during development: fetal and adult Leydig cells (FLCs and ALCs, respectively). ALCs are not derived from FLCs, and it is unknown whether these two populations share common progenitors. We discovered that hedgehog (Hh)
Vivi F H Jensen et al.
Scientific reports, 10(1), 5609-5609 (2020-03-30)
Maternal hypoglycaemia throughout gestation until gestation day (GD)20 delays foetal growth and skeletal development. While partially prevented by return to normoglycaemia after completed organogenesis (GD17), underlying mechanisms are not fully understood. Here, we investigated the pathogenesis of these changes and
Global but not gonadotrope-specific disruption of Bmal1 abolishes the luteinizing hormone surge without affecting ovulation.
Chu, A; Zhu, L; Blum, ID; Mai, O; Leliavski, A; Fahrenkrug, J; Oster, H; Boehm, U; Storch, KF
Endocrinology null
Irene Cimino et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(27) (2021-07-01)
An acute increase in the circulating concentration of glucocorticoid hormones is essential for the survival of severe somatic stresses. Circulating concentrations of GDF15, a hormone that acts in the brain to reduce food intake, are frequently elevated in stressful states.
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