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安全信息

RKTX2MAG-37K

Millipore

MILLIPLEX® 大鼠肾毒性磁珠面板2-毒性多重测定

The analytes available for this multiplex kit are: Albumin, AGP, ß2M, Cystatin C, EGF, Lipocalin-2/NGAL.

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UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.84

质量水平

200

种属反应性

rat

制造商/商品名称

Milliplex®

assay range

accuracy: 70-123%
standard curve range: 0.00-2 ng/mL
(EGF)
standard curve range: 0.01-10 ng/mL
(Lipocalin-2/NGAL)
standard curve range: 0.01-8 ng/mL
(Cystatin C)
standard curve range: 0.48-350 ng/mL
(β2M)
standard curve range: 1.37-1,000 ng/mL
(AGP)
standard curve range: 10.97-8,000 ng/mL
(Albumin)
inter-assay cv: <15%
intra-assay cv: <10%
(All other analytes)
inter-assay cv: <20%
intra-assay cv: <15%
(AGP)

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

相关类别

一般描述

MILLIPLEX® 大鼠肾毒性磁珠面板1 & 2，加上微珠形式的Luminex® xMAP®平台，使您能够专注于发现，从而获得理想的速度和灵敏度优势，允许同时定量多重检测多种分析物，从而可以显著提高生产力。

面板类型：毒性

特异性

针对一种分析物的抗体与该组中的任何其他分析物之间不存在或可忽略的交叉反应性。

应用

  • 分析物：α-1酸性糖蛋白(AGP)、白蛋白、ß2M、胱抑素C、EGF、Lipocalin-2/NGAL
  • 推荐的样品类型：尿液
  • 推荐的样品稀释度：1:500
  • 分析运行时间：过夜
  • 研究类别：毒性

特点和优势

通过在此面板中选择可用的分析物来设计多重试剂盒。

包装

单个试剂盒即可满足您的所有需求。

储存及稳定性

试剂盒组分建议的存储温度为2-8°C。

其他说明

灵敏度：有关单个分析物的灵敏度，请参见试剂盒方案。

法律信息

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

象形图

Skull and crossbonesEnvironment
GHS06,GHS09

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

法规信息

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Michael J Coyne et al.
PloS one, 17(5), e0269085-e0269085 (2022-05-28)
Symmetric dimethylarginine (SDMA) is a serum biomarker of excretory renal function which consistently correlates with glomerular filtration rate (GFR) across multiple species including rats, dogs, and humans. In human and veterinary clinical settings SDMA demonstrates enhanced sensitivity for detection of
Mónica Ríos-Silva et al.
Molecules (Basel, Switzerland), 24(1) (2018-12-26)
Capsaicin is an agonist of the transient receptor potential vanilloid type 1 (TRPV1) channel, which has been related to the pathophysiology of kidney disease secondary to diabetes. This study aimed to evaluate the chronic effect of capsaicin administration on biomarkers
Kidney biomarkers in MCPA-induced acute kidney injury in rats: reduced clearance enhances early biomarker performance.
Wunnapuk, K; Liu, X; Gobe, GC; Endre, ZH; Peake, PW; Grice, JE; Roberts, MS; Buckley, NA
Toxicology Letters null
Iwan P Williams et al.
mAbs, 12(1), 1685349-1685349 (2019-11-27)
IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to human exposure and
Nadeeka S Udawatte et al.
Frontiers in pharmacology, 11, 511-511 (2020-05-12)
Candida albicans is the major fungal species associated with superficial mucosal infections such as oral candidiasis as well as systemic mycoses with high morbidity and mortality. On top of the rising drug resistance, currently available antifungal agents have significant adverse
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