MILLIPLEX^® Non-Human Primate Cytokine/Chemokine/Growth Factor Panel A

Cytokines are small proteins secreted by immune cells that regulate immune responses, hematopoiesis, and lymphocyte development, including interleukins, interferons, and chemokines. Growth factors, which promote cell growth and proliferation, share structural and functional similarities with cytokines and act through specific receptors on target cells. Unlike hormones produced by specialized glands, both cytokines and growth factors can be secreted by various cell types, and their tightly regulated expression is crucial; dysregulation can lead to diseases such as infections, autoimmune disorders, and cancer. Research on these molecules is essential for understanding the immune system and developing therapeutic strategies, with non-human primates serving as important models due to their genetic similarity to humans.

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 38 analytes in non-human primate serum, plasma, and cell culture supernatants.

Analytes included: sCD137, CD40L, sFASL, G-CSF, GM-CSF, Granzyme A, Granzyme B, IFNα2, IFNγ, IL-1β, IL-1RA, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p70), IL-15, IL-17A, IL-18, IL-21, IL-22, IL-23, IL-33, IP-10, I-TAC, MCP-1, MIG, MIP-1α, MIP-1β, MIP-3α, Perforin, RANTES, TGFα, TNFα, VEGF-A

Note: RANTES cannot be plexed with other cytokines in this panel due to a required 1:100 dilution of plasma/serum samples. This premixed panel comes with a RANTES bead, so please plan your samples accordingly.

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Optimized for Primate Immunology: Designed to meet the unique requirements of non-human primate models, facilitating advanced immunological and biomedical investigations.

Streamlined Workflow with Premixed Reagents: Simplify your assay process with premixed components that eliminate prep steps and reduce the risk of pipetting errors.

Flexible Sample Types: Works with serum, plasma, tissue/cell culture lysates and culture supernatants, making it ideal for diverse experimental setups.

User-Friendly Protocol: Clear, step-by-step instructions make the kit accessible to both experienced researchers and new lab personnel.

Efficient Sample Use: Low sample volume requirement makes it suitable for studies with limited biological material.

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.