推荐产品
生物来源
rabbit
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
liquid
不包含
preservative
种属反应性
human, mouse
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
avoid repeated freeze/thaw cycles
同位素/亚型
IgG
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MSH2(4436)
一般描述
Purified rabbit polyclonal antibody. Recognizes the ~100 kDa MSH2 protein.
Recognizes the ~100 kDa MSH2 protein in HCT116 and SW480 cells and in colon tissue.
This Anti-MSH2 (Ab-3) Rabbit pAb is validated for use in Frozen Sections, Immunoblotting, Immunoprecipitation, Paraffin Sections for the detection of MSH2 (Ab-3).
免疫原
full length, recombinant, human MSH2
应用
Frozen Sections (2 µg/ml)
Immunoblotting (1 µg/ml, chemiluminescence)
Immunoprecipitation (1 µg/sample)
Paraffin Sections (see application references)
Immunoblotting (1 µg/ml, chemiluminescence)
Immunoprecipitation (1 µg/sample)
Paraffin Sections (see application references)
包装
Please refer to vial label for lot-specific concentration.
警告
Toxicity: Standard Handling (A)
其他说明
Bronner, C.E., et al. 1994. Nature368, 258.
Papadopoulos, N., et al. Science263, 1625.
Peltomäki, P.T. 1994. Ann. Medicine26, 215.
Fishel, R., et al. 1993. Cell75, 1027.
Leach, F.S., et al. 1993. Cell75, 1215.
Lindbolm, A., et al. 1993. Nat. Genet.5, 279.
Papadopoulos, N., et al. Science263, 1625.
Peltomäki, P.T. 1994. Ann. Medicine26, 215.
Fishel, R., et al. 1993. Cell75, 1027.
Leach, F.S., et al. 1993. Cell75, 1215.
Lindbolm, A., et al. 1993. Nat. Genet.5, 279.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
J Barwell et al.
Journal of medical genetics, 44(8), 516-520 (2007-05-08)
Reports of differential mutagen sensitivity conferred by a defect in the mismatch repair (MMR) pathway are inconsistent in their conclusions. Previous studies have investigated cells established from immortalised human colorectal tumour lines or cells from animal models. We examined primary
Jennifer L Cyr et al.
Molecular carcinogenesis, 51(8), 647-658 (2011-08-13)
Lynch syndrome (LS) is caused by germline mutations in DNA mismatch repair (MMR) genes. MMR recognizes and repairs DNA mismatches and small insertion/deletion loops. Carriers of MMR gene variants have a high risk of developing colorectal, endometrial, ovarian, and other
Jennifer A McKinney et al.
Nature communications, 11(1), 236-236 (2020-01-15)
Alternative DNA structure-forming sequences can stimulate mutagenesis and are enriched at mutation hotspots in human cancer genomes, implicating them in disease etiology. However, the mechanisms involved are not well characterized. Here, we discover that Z-DNA is mutagenic in yeast as
Samar Hassen et al.
Journal of experimental & clinical cancer research : CR, 30, 100-100 (2011-10-25)
A broad population-based assay to detect individuals with Lynch Syndrome (LS) before they develop cancer would save lives and healthcare dollars via cancer prevention. LS is caused by a germline mutation in a DNA mismatch repair (MMR) gene, especially protein
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门