产品名称
Anti-Porin (Ab-5) (185-197) Rabbit pAb, liquid, Calbiochem®
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human, rat
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
dilution
(Immunoblotting (2 µg/mL))
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... VDAC1(7416)
Analysis Note
Positive Control
Rat heart tissue
Rat heart tissue
Application
Immunoblotting (2 g/ml)
Disclaimer
Toxicity: Standard Handling (A)
General description
Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~31 kDa (VDAC) porin protein.
Recognizes the ~31 kDa porin protein.
This Anti-Porin (Ab-5) (185-197) Rabbit pAb is validated for use in Immunoblotting for the detection of Porin (Ab-5) (185-197).
Immunogen
Human
a synthetic peptide corresponding to amino acids 185-197 of human porin
Other Notes
Crompton, M., et al. 1999. Biochem. J.341, 233.
Yu, W.H., et al. 1995. J. Biol. Chem.270, 13998.
McEnry, M.W., et al. 1993. J. Biol. Chem.268, 23289.
Yu, W.H., et al. 1995. J. Biol. Chem.270, 13998.
McEnry, M.W., et al. 1993. J. Biol. Chem.268, 23289.
The immunogen peptide is 100% conserved in all three isoforms of VDAC (VDAC1, VDAC2, and VDAC3). Antibody should be titrated for optimal results in individual systems.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In PBS, 1 mg/ml BSA.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Theresa Schöttl et al.
Molecular metabolism, 4(9), 631-642 (2015-09-29)
Several human and rodent obesity studies speculate on a causal link between altered white adipocyte mitochondria in the obese state and changes in glucose homeostasis. We here aimed to dissect whether alterations in white adipocyte mitochondrial respiratory function are a
Takahiro Ishiwata et al.
PloS one, 7(8), e42118-e42118 (2012-08-08)
CryAB (HspB5) and HspB2, two small heat shock genes located adjacently in the vertebrate genome, are hypothesized to play distinct roles. Mice lacking both cryab and hspb2 (DKO) are viable and exhibit adult-onset degeneration of skeletal muscle but confounding results
Xiaoxiao Peng et al.
Scientific reports, 6, 28080-28080 (2016-06-28)
Recently thioredoxin reductase 1 (TrxR1), encoded by Txnrd1, was suggested to modulate glucose and lipid metabolism in mice. Here we discovered that TrxR1 suppresses insulin responsiveness, anabolic metabolism and adipocyte differentiation. Immortalized mouse embryonic fibroblasts (MEFs) lacking Txnrd1 (Txnrd1(-/-)) displayed
Sergei A Novgorodov et al.
The Journal of biological chemistry, 286(28), 25352-25362 (2011-05-27)
Reports suggest that excessive ceramide accumulation in mitochondria is required to initiate the intrinsic apoptotic pathway and subsequent cell death, but how ceramide accumulates is unclear. Here we report that liver mitochondria exhibit ceramide formation from sphingosine and palmitoyl-CoA and
Alfredo Criollo et al.
Apoptosis : an international journal on programmed cell death, 12(1), 3-18 (2006-11-03)
HeLa and HCT116 cells respond differentially to sorbitol, an osmolyte able to induce hypertonic stress. In these models, sorbitol promoted the phenotypic manifestations of early apoptosis followed by complete loss of viability in a time-, dose-, and cell type-specific fashion
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持