一般描述
Purified mouse monoclonal antibody generated by immunizing BALB/c mice with the specified immunogen and fusing splenocytes with NS-1 mouse myeloma cells. Recognizes the ~105 kDa Rb protein.
Recognizes the ~105 kDa Rb protein. Sold under license of U.S. Patent 5,853,988 and corresponding patents.
This Anti-Rb (Ab-5) Mouse mAb (LM95.1) is validated for use in Immunoblotting, Paraffin Sections for the detection of Rb (Ab-5).
免疫原
Epitope: within a 56 kDa C-terminal fragment
Human
recombinant, human Rb
应用
Immunoblotting (1 µg/ml; see application references)
Paraffin Sections (3 µg/ml, see comments and application references)
Paraffin Sections (3 µg/ml, see comments and application references)
包装
Please refer to vial label for lot-specific concentration.
外形
In 50 mM sodium phosphate buffer, 0.2% gelatin.
分析说明
Negative Control
Saos cells
Saos cells
Positive Control
ML-1 cells or normal colon tissue
ML-1 cells or normal colon tissue
其他说明
Dyson, N., et al. 1992. J. Virol.66, 4606.
Dyson, N., et al. 1990. J. Virol.64, 1353.
Horowitz, J.M., et al. 1989. Science243, 937.
Whyte, P., et al. 1988. Nature334, 124.
Klein, G. 1987. Science238, 1539.
Lee, W.H., et al. 1987. Science235, 1394.
Lee, W.H., et al. 1987. Nature329, 642.
Knudson, A.G. 1971. Proc. Natl. Acad. Sci. USA68, 820.
Dyson, N., et al. 1990. J. Virol.64, 1353.
Horowitz, J.M., et al. 1989. Science243, 937.
Whyte, P., et al. 1988. Nature334, 124.
Klein, G. 1987. Science238, 1539.
Lee, W.H., et al. 1987. Science235, 1394.
Lee, W.H., et al. 1987. Nature329, 642.
Knudson, A.G. 1971. Proc. Natl. Acad. Sci. USA68, 820.
Pre-treatment with heat or pressure cooker may improve staining of some tissue specimens; this should be determined for each specimen. Antibody should be titrated for optimal results in individual systems.
法律信息
Sold under license of U.S. Patent 5,853,988 and corresponding patents.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
含少量动物源组分生物产品
此项目有
Abstracts from USCAP 2019: Genitourinary Pathology (including renal tumors) (776-992).
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 32(Suppl 2), 1-173 (2019-03-20)
Nora M Navone et al.
The Prostate, 78(16), 1262-1282 (2018-08-04)
While it has been challenging to establish prostate cancer patient-derived xenografts (PDXs), with a take rate of 10-40% and long latency time, multiple groups throughout the world have developed methods for the successful establishment of serially transplantable human prostate cancer
Jeong Namkung et al.
The Journal of clinical endocrinology and metabolism, 97(9), 3224-3230 (2012-07-05)
Müllerian inhibiting substance (MIS) is produced in Sertoli cells of fetal testis and causes regression of müllerian ducts in male embryos. MIS also can induce the cell cycle arrest and apoptosis in müllerian duct-derived tumors in vivo and in vitro.
Frédéric Dallaire et al.
mSphere, 1(1) (2016-06-16)
Human adenovirus (Ad) E1A proteins have long been known as the central regulators of virus infection as well as the major source of adenovirus oncogenic potential. Not only do they activate expression of other early viral genes, they make viral
Michael T Tetzlaff et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 25(4), 1280-1290 (2018-11-14)
Ocular adnexal (OA) sebaceous carcinoma is an aggressive malignancy of the eyelid and ocular adnexa that frequently recurs and metastasizes, and effective therapies beyond surgical excision are lacking. There remains a critical need to define the molecular-genetic drivers of the
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持