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MTH17MAG-47K

Millipore

MILLIPLEX®小鼠TH17磁珠组套 - 免疫学多重检测试剂盒

Simultaneously analyze multiple Th17 cytokine and chemokine biomarkers with the Th17 Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.

别名:

Luminex® Mouse Immunology Panel, Millipore Mouse Immunology Panel, Mouse Immunology Protein Multiplex Assay

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About This Item

UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.84

质量水平

200

种属反应性

mouse

制造商/商品名称

Milliplex®

assay range

linearity: 111.0%
(1:04)
linearity: 113.1%
(1:08)
standard curve range: 1.5-1,500 pg/mL
(IL-4)
standard curve range: 10-10,000 pg/mL
(IL-17F)
standard curve range: 127-130,000 pg/mL
(IL-28B)
standard curve range: 15-15,000 pg/mL
(IL-1β)
standard curve range: 2.4-2,500 pg/mL
(IL-22)
standard curve range: 20-20,000 pg/mL
(IL-10, IL-12(p70), & IL-21)
standard curve range: 3.4-3,500 pg/mL
(TNFα)
standard curve range: 34-35,000 pg/mL
(GM-CSF & IL-15)
standard curve range: 342-350,000 pg/mL
(IL-23)
standard curve range: 39-40,000 pg/mL
(IL-13 & IL-17A)
standard curve range: 4.9-5,000 pg/mL
(IL-5)
standard curve range: 488-500,000 pg/mL
(TNFβ)
standard curve range: 49-50,000 pg/mL
(CD40L IL-31 & MIP-3α)
standard curve range: 586-600,000 pg/mL
(IL-17E/ IL-25)
standard curve range: 6.9-6,000 pg/mL
(IL-2)
standard curve range: 7.8-8,000 pg/mL
(IFNγ & IL-6)
standard curve range: 78-80,000 pg/mL
(IL-33)
standard curve range: 879-900,000 pg/mL
(IL-27)

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

相关类别

一般描述

MILLIPLEX®小鼠Th17珠组套使您能够专注于调节CD4 T辅助细胞细胞因子的治疗潜力。结合微珠格式的Luminex ® xMAP®平台，您可以获得理想的速度和灵敏度的优势，允许同时对数十种分析物进行定量多重检测，从而可以显著提高生产力。

组套类型：细胞因子/趋化因子

特异性

交叉反应性
抗体与样品组中的任何其他分析物之间没有交叉反应性或交叉反应性最小（请参见测定方案中的详细信息）。

应用

  • 分析物：CD40配体、GM-CSF、IFN-γ、IL-1β、IL-2、IL-4、IL-5、IL-6、IL-10、IL-12（p70）、IL-13、IL-15、IL-17A、IL-17E/IL-25、IL-17F、IL-21、IL-22、IL-23、IL-27、IL-28B、IL-31、IL-33、MIP-3α/CCL20、TNF-α、TNFβ
  • 建议的样品类型：血清、血浆或组织/细胞裂解物和培养物上清液
  • 建议的样品稀释度：纯品
  • 测定运行时间：过夜或一天
  • 研究类别：炎症&免疫学

特点和优势

通过在此组套中选择可用的分析物来设计多重试剂盒。

储存及稳定性

试剂盒组件的建议储存温度为2 - 8°C。

其他说明

灵敏度：有关单个生物标志物的灵敏度，请参阅试剂盒方案。

法律信息

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免责声明

除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。

警示用语：

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

靶器官

Respiratory Tract

储存分类代码

10 - Combustible liquids

法规信息

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Mohammad Afzal Khan et al.
Cells, 10(5) (2021-06-03)
Interleukin-10 plays a vital role in maintaining peripheral immunotolerance and favors a regulatory immune milieu through the suppression of T effector cells. Inflammation-induced microvascular loss has been associated with airway epithelial injury, which is a key pathological source of graft
Mohammad Afzal Khan et al.
Frontiers in immunology, 9, 1010-1010 (2018-06-09)
Microvascular injury during acute rejection has been associated with massive infiltration of CD4+ T effector cells, and the formation of complement products (C3a and C5a). Regulatory T cells (Tregs) are potent immunosuppressors of the adaptive immune system and have proven
M John Albert et al.
Scientific reports, 9(1), 12024-12024 (2019-08-21)
There is no information on cytokine profiles for use as markers of protection in Campylobacter jejuni infection. To study this, we used outer membrane protein (MOMP [PorA]) as the vaccine for protection and spleen cell cytokines as markers of protection.
Sarah J Dulson et al.
Journal of immunology (Baltimore, Md. : 1950), 203(9), 2472-2484 (2019-09-29)
Innate lymphoid cells (ILCs) are strategically positioned at mucosal barrier surfaces where they respond quickly to infection or injury. Therefore, we hypothesized that ILCs are key contributors to the early immune response in the intestine against Listeria monocytogenes Using a
Anthony Tam et al.
Cells, 11(19) (2022-10-15)
Genome-wide association studies (GWAS) have shown that variants of patched homolog 1 (PTCH1) are associated with lung function abnormalities in the general population. It has also been shown that sonic hedgehog (SHH), an important ligand for PTCH1, is upregulated in
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