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MMMP2MAG-79K

Millipore

MILLIPLEX® Mouse MMP Magnetic Bead Panel 2 - Immunology Multiplex Assay

TIMP Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple TIMP biomarkers in mouse serum, plasma and cell culture samples.

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About This Item

UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.84
To order a Milliplex® kit, please search for your analyte of interest.
Design And Price Your Kit

质量水平

200

种属反应性

mouse

制造商/商品名称

Milliplex®

assay range

standard curve range: 12-50,000 pg/mL
(proMMP-9)
standard curve range: 5-20,000 pg/mL
(MMP-12)

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

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MILLIPLEX® Mouse MMP Magnetic Bead Panel 2 - Immunology Multiplex Assay TIMP Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple TIMP biomarkers in mouse serum, plasma and cell culture samples.

MMMP2MAG79K

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MMMP3MAG79K

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MILLIPLEX® 人MMP磁珠板2-免疫学多重检测 Matrix Metalloproteinase Bead-Based Multiplex Assays using the Luminex technology enable the simultaneous analysis of multiple MMPs biomarkers in human serum, plasma and cell culture samples.

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MILLIPLEX® Human MMP Magnetic Bead Panel 1 - Immunology Multiplex Assay Matrix Metalloproteinase Bead-Based Multiplex Assays using the Luminex technology enable the simultaneous analysis of multiple MMPs biomarkers in human serum, plasma and cell culture samples.

HMMP1MAG55K

MILLIPLEX® Human MMP Magnetic Bead Panel 1 - Immunology Multiplex Assay

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

assay range

standard curve range: 12-50,000 pg/mL
(proMMP-9), standard curve range: 5-20,000 pg/mL
(MMP-12)

assay range

standard curve range: 12-50,000 pg/mL
(MMP-8), standard curve range: 12-50,000 pg/mL
(proMMP-9), standard curve range: 2-10,000 pg/mL
(MMP-3), standard curve range: 49-200,000 pg/mL
(MMP-2), standard curve range: 5-20,000 pg/mL
(MMP-12)

assay range

-

assay range

standard curve range: 146-150,000 pg/mL
(MMP-3), standard curve range: 58-60,000 pg/mL
(MMP-13), standard curve range: 98-100,000 pg/mL
(MMP-12)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

一般描述

The MMPs (matrix metalloproteinases), a family of zinc proteases responsible for the breakdown of extracellular matrix (ECM), play a key role in normal physiological processes, such as embryonic development and tissue morphogenesis, tissue and bone remodeling, wound healing, and angiogenesis. These processes rely on MMPs′ role in the cleavage of cell surface receptors, the release of apoptotic ligands, cell proliferation and differentiation, and chemokine activity modulation. Similar in structure, MMPs are synthesized and secreted as inactive pro-enzymes that require proteolytic cleavage for activation. This process can be mediated by serine proteases or other MMPs. An increase in MMP expression occurs in response to a wide range of stimuli, including adhesion molecules, growth factors, cytokines, and hormones. Regulation of MMP activity is controlled primarily by TIMPs (tissue inhibitors of metalloproteinases). Therefore, disruption of the MMP/TIMP balance can result in autoimmune disease, arthritis, cardiovascular disease, and tumor growth and metastasis.

MILLIPLEX® Mouse MMP Bead Panel 2, MMMP2MAG-79K, is a 2 plex kit to be used for the simultaneous quantification of the following analytes in serum/plasma samples: proMMP-9 and MMP-12.

Panel Type: Cytokines/Chemokines

特异性

Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

应用

  • Analytes: proMMP-9, MMP-12
  • Recommended Sample type: serum or plasma
  • Recommended Sample dilution: 1:2
  • Assay Run Time: overnight or one day
  • Research Category: Inflammation & Immunology

特点和优势

Design your multiplex kit by choosing available analytes within this panel.

储存及稳定性

Recommended storage for kit components is 2 - 8°C.

其他说明

Sensitivity: See protocol for sensitive’s of individual analytes

法律信息

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

警示用语：

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

靶器官

Respiratory Tract

储存分类代码

10 - Combustible liquids

法规信息

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    Alexandra Noël et al.
    Frontiers in physiology, 12, 704401-704401 (2021-12-17)
    Matrix metalloproteinase-12 (Mmp12) is upregulated by cigarette smoke (CS) and plays a critical role in extracellular matrix remodeling, a key mechanism involved in physiological repair processes, and in the pathogenesis of emphysema, asthma, and lung cancer. While cigarette smoking is

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