MABT61
Anti-Nectin-1/PVRL1 (CD111) Antibody, clone R1.302
clone R1.302.12, from mouse
别名:
poliovirus receptor-related 1 (herpesvirus entry mediator C), nectin-1, poliovirus receptor-related protein 1, poliovirus receptor-like 1, nectin 1, ectodermal dysplasia 4 (Margarita Island type), Herpesvirus entry mediator C, Herpes virus entry mediator
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所有图片(1)
About This Item
UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
推荐产品
生物来源
mouse
质量水平
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
R1.302.12, monoclonal
种属反应性
human
技术
flow cytometry: suitable
immunofluorescence: suitable
同位素/亚型
IgG1κ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... PVRL1(5818)
相关类别
一般描述
Nectin-1, also known as poliovirus receptor-related protein 1 (PRR1 or PVRL1) or CD111, is an immunoglobulin-like transmembrane cell adhesion protein that also seems to play a role in neural tube formation, with N-cadherin. Nectins are known for being the receptors for the herpes simplex virus. Nectin-1 is connected with the actin cytoskeleton through afadin inside the cell. It is predominantly found in human placenta although in mice, expression is wide-ranging. Nectin-1 seems to adhere primarily to cells expressing nectin-4 and vice versa.
免疫原
Human CD111 transfected NIH/3T3 cells
应用
Immunofluorescence Analysis: A previous lot was used by an independent laboratory in IF (Cocchi, F., et al. (1998). Journal of Virology. 72(12):9992–10002).
This Anti-Nectin-1/PVRL1 (CD111) Antibody, clone R1.302 is validated for use in FC, IF for the detection of Nectin-1/PVRL1 (CD111).
质量
Evaluated by Flow Cytometry in human TF-1 cells.
Flow Cytometry Analysis: 0.25 µg of this antibody detected Nectin-1/PVRL1 in human TF-1 cells.
Flow Cytometry Analysis: 0.25 µg of this antibody detected Nectin-1/PVRL1 in human TF-1 cells.
目标描述
57 kDa calculated
外形
Format: Purified
分析说明
Control
Human TF-1 cells
Human TF-1 cells
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Kristin L M Boylan et al.
Oncotarget, 8(6), 9717-9738 (2016-12-31)
The cell adhesion molecule Nectin-4 is overexpressed in epithelial cancers, including ovarian cancer. The objective of this study was to determine the biological significance of Nectin-4 in the adhesion, aggregation, migration, and proliferation of ovarian cancer cells. Nectin-4 and its
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