MABT108
Anti-TNF-alpha induced protein 6 (TSG-6) Antibody, clone NG3
clone NG3, from mouse
别名:
Tumor necrosis factor-inducible gene 6 protein, TNF-stimulated gene 6 protein, TSG-6, Tumor necrosis factor alpha-induced protein 6, TNF alpha-induced protein 6
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所有图片(1)
About This Item
UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
一般描述
Tumor Necrosis Factor-alpha (TNF-alpha), also known as TSG-6, is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. The mature form of human TNF-alpha has 157 amino acid residues. TNF-alpha induced protein 6 may be involved in cell-cell and cell-matrix interactions during normal inflammatory responses and during tumorigenesis.
特异性
Published to react with human TSG-6 (Nagyeri, G., et al. (2011). JBC. PMID: 21566135).
免疫原
Epitope: Unknown
GST-tagged recombinant protein corresponding to mouse TSG-6.
应用
Detect TNF-alpha induced protein 6 (TSG-6) using this Anti-TNF alpha Antibody, clone NG3 validated for use in WB, ELISA. This TNF alpha antibody has been tested in Human and Mouse.
ELISA: A previous lot of this antibody was used in capture ELISA to demonstrate a typical standard curve for measuring TSG6 from normal (naïve) serum.
Western Blot Analysis: A previous lot of this antibody was show to detect human or mouse samples (Nagyeri, G., et al. (2011). JBC. PMID: 21566135).
Western Blot Analysis: A previous lot of this antibody was show to detect human or mouse samples (Nagyeri, G., et al. (2011). JBC. PMID: 21566135).
Research Category
Cell Structure
Cell Structure
Research Sub Category
ECM Proteins
ECM Proteins
质量
Evaluated by Western Blot in mouse ovary tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected TSG-6 in 10 µg of mouse ovary tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected TSG-6 in 10 µg of mouse ovary tissue lysate.
目标描述
~29 kDa observed.
An uncharacterized band appears at ~50 kDa in some lysates.
An uncharacterized band appears at ~50 kDa in some lysates.
外形
Protein G Purified
Format: Purified
Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Mouse ovary tissue lysate
Mouse ovary tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
F E Watt et al.
Osteoarthritis and cartilage, 28(3), 324-333 (2020-01-07)
Surgical knee joint distraction (KJD) leads to clinical improvement in knee osteoarthritis (OA) and also apparent cartilage regeneration by magnetic resonance imaging. We investigated if alteration of the joint's mechanical environment during the 6 week period of KJD was associated
Fiona E Watt et al.
Arthritis & rheumatology (Hoboken, N.J.), 68(9), 2129-2140 (2016-03-19)
To investigate whether molecules found to be up-regulated within hours of surgical joint destabilization in the mouse are also elevated in the analogous human setting of acute knee injury, how this molecular response varies between individuals, and whether it is
Chiara Di Santo et al.
International journal of molecular sciences, 24(6) (2023-03-30)
The identification of novel targets to modulate the immune response triggered by cerebral ischemia is crucial to promote the development of effective stroke therapeutics. Since tumour necrosis factor (TNF)-α-stimulated gene 6 (TSG-6), a hyaluronate (HA)-binding protein, is involved in the
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