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生物来源
mouse
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
6.3, monoclonal
种属反应性(根据同源性预测)
all
包装
antibody small pack of 25 μg
技术
ELISA: suitable
同位素/亚型
IgG1κ
靶向翻译后修饰
unmodified
一般描述
Polyethylene glycols (PEG) are non-toxic, uncharged, hydrophilic long chain polymers with a big exclusion volume in aqueous solution. The covalent attachment of PEG is commonly employed to modify proteins and drugs that can increase their bioavailability and reduce immunogenicity and proteolytic degradation. Clone 6.3 displays high affinity and binds the PEG backbone and can be employed as a detection antibody for the quantification of PEG. It binds to a smaller epitope of the PEG backbone when compared to other antibodies. Since it binds to a smaller PEG epitope (~750 Da), it is not compatible with detergents that contain an ethylene oxide backbone, such as Tween 20. Instead 0.05% CHAPS is a more suitable detergent when using this antibody.
特异性
Clone 6.3 specifically detects proteins conjugated with polyethylene glycol (PEG).
免疫原
PEG-conjugated to E.coli beta-glucuronidase.
应用
Anti-PEG, clone 6.3, Cat. No. MABS1966, is a mouse monoclonal antibody that detects PEG-conjugated proteins and it hs been tested for use in ELISA.
ELISA Analysis: A representative lot detected PEG in ELISA applications (Tung, H.Y., et. al. (2015). Mol Cancer Ther. 14(6):1317-26).
Research Category
Signaling
Signaling
质量
Evaluated by ELISA in Immobilized PEG (10K-PEG, 3K-PEG, and 2K-mPEG).
ELISA Analysis: 5 µg/mL of Immobilized PEG (10K-PEG, 3K-PEG, and 2K-mPEG) were detected with this antibody.
ELISA Analysis: 5 µg/mL of Immobilized PEG (10K-PEG, 3K-PEG, and 2K-mPEG) were detected with this antibody.
外形
Protein A purified
Format: Purified
Purified mouse monoclonal antibody IgG1 in PBS with 0.04% sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to lot specific datasheet.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
法规信息
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