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主要文件

MABN92-AF647

Sigma-Aldrich

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor 647 Conjugate

clone 20A12.1, from mouse, ALEXA FLUOR 647

别名:

Allograft inflammatory factor 1, AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.45

生物来源

mouse

质量水平

偶联物

ALEXA FLUOR 647

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

20A12.1, monoclonal

种属反应性

mouse, human, rat

技术

immunofluorescence: suitable

同位素/亚型

IgG1κ

NCBI登记号

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聚乙二醇 3000, for synthesis

819015

聚乙二醇

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

2-30°C

storage temp.

no temp limit

storage temp.

no temp limit

storage temp.

2-30°C

mp

58-63 °C

mp

58-63 °C

mp

17-22 °C

mp

55-58 °C

transition temp

flash point 270 °C

transition temp

flash point 265 °C

transition temp

flash point 260 °C

transition temp

flash point 270 °C

density

1.2 g/cm3 at 20 °C

density

1.2 g/cm3 at 20 °C

density

1.13 g/cm3 at 20 °C

density

1.21 g/cm3 at 20 °C

一般描述

Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.

应用

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor 647 Conjugate is an antibody against AIF1 for use in Immunofluorescence.
The unconjugated antibody (Cat. No. MABN92) is shown to be suitable also for Western blotting and immunohistochemistry applications.

质量

Evaluated by Immunofluorescence in human spleen tissue.

Immunofluorescence Analysis: A 1:50 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.

目标描述

~17 kDa observed.

其他说明

Concentration: Please refer to lot specific datasheet.

法律信息

ALEXA FLUOR is a trademark of Life Technologies

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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