Anti-α-Synuclein (SNCA) Antibody

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected α-syn in 10 µg of human brain tissue lysate.

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected α-syn in human cerebral cortex tissue.
Western Blotting Analysis: A representative lot detected α-syn in PK-digested FL a-syn pffs (Guo, J.L., et al. (2013). Cell. 154:103-117).

This antibody detects a-Synuclein preformed fibrils that can cross seed tau fibrilliation.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Conjugated linear peptide corresponding to human α-syn (aa 115-122).

~15 kDa observed

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.