推荐产品
生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
L5/1, monoclonal
种属反应性
rat, human
种属反应性（根据同源性预测）
mouse (based on 100% sequence homology)
技术
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型
IgG2bκ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
rat ... Stmn2(84510)
一般描述
Stathmin-like 2 (STMN2) protein is a phospho-protein and functions in microtubule dynamics and signal transduction. Studies show STMN2 plays a regulatory role in neuronal growth and thought to be involved in osteogenesis. Reduced levels, i.e. reduction in expression, have been associated with Down′s syndrome and Alzheimer′s disease. Data also suggests that STMN2 may play a role in modulating membrane interaction with the cytoskeleton during neurite outgrowth.
免疫原
Epitope: C-terminus
Linear peptide corresponding to the C-terminus of rat STMN2.
应用
Detect STMN using this mouse monoclonal antibody, Anti-STMN2 Antibody, clone L5/1 validated for use in western blotting, IHC & ICC.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Signaling
Developmental Signaling
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected STMN2 in 10 µg of rat fetal brain (E16) tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected STMN2 in rat hippocampus tissue.
Immunocytochemistry Analysis: A representative lot detected STMN2 in cultured hippocampal neurons (Prof. J. Trimmer, University of Califnornia, Davis.).
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected STMN2 in rat hippocampus tissue.
Immunocytochemistry Analysis: A representative lot detected STMN2 in cultured hippocampal neurons (Prof. J. Trimmer, University of Califnornia, Davis.).
质量
Evaluated by Western Blotting in SH-SY-5Y cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected STMN2 in 10 µg of SH-SY-5Y cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected STMN2 in 10 µg of SH-SY-5Y cell lysate.
目标描述
~21 kDa observed
外形
Protein G Purified
Format: Purified
Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Daisuke Aoki et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(4), 1473-1480 (2009-02-21)
Of the various microtubule-associated molecules, beta-tubulin III has been reported to be closely associated with the therapeutic efficacy of taxane-based chemotherapy against ovarian cancer. Stathmin and microtubule-associated protein 4 (MAP4) have been reported to play an important role in microtubule
Meghna Kannan et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(44), E9308-E9317 (2017-10-29)
The family of WD40-repeat (WDR) proteins is one of the largest in eukaryotes, but little is known about their function in brain development. Among 26 WDR genes assessed, we found 7 displaying a major impact in neuronal morphology when inactivated
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门