生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
3D9, monoclonal
种属反应性
rat
种属反应性（根据同源性预测）
human (immunogen homology)
技术
immunocytochemistry: suitable
western blot: suitable
同位素/亚型
IgMκ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... DRD2(1813)
rat ... Drd2(24318)
一般描述
中枢神经系统多巴胺能系统的问题被认为是某些神经精神疾病的根本原因。多巴胺D2受体是多巴胺的五种类型（D1至D5）受体之一。该受体的活性由抑制腺苷酸环化酶的G蛋白介导。使用Nurr1和ERK的多巴胺D2受体信号传导可能在中脑多巴胺能神经元发育中起重要作用。有缺陷的D2受体在ROS依赖性高血压病例中很常见。此外，DRD2的缺陷与酒精反应性肌张力障碍，对家族性酒精中毒的易感性不同以及酗酒者自杀风险的促成因素有关。
免疫原
对应于人多巴胺D2受体的线性肽。
应用
免疫细胞化学分析：独立实验室使用了一个先前批次来检测Ntera-2细胞和大鼠脑神经元中的多巴胺D2受体。 由Wolfson Centre for Inherited Neuromuscular Disease的Glenn Morris提供。
经验证，该抗多巴胺D2受体（DRD2）抗体（克隆2B9）可用于检测多巴胺D2受体（DRD2）的WB、IC。
质量
通过蛋白质印迹法在大鼠脊髓组织裂解物中进行评估。
蛋白质印迹分析：5 µg/mL的该抗体在10 µg大鼠脊髓组织裂解物上检测到多巴胺D2受体。
蛋白质印迹分析：5 µg/mL的该抗体在10 µg大鼠脊髓组织裂解物上检测到多巴胺D2受体。
目标描述
观测分子量〜50 kDa
外形
形式：纯化
分析说明
对照
大鼠脊髓组织裂解物
大鼠脊髓组织裂解物
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WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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