MABN287
Anti-ABCA4 Antibody, clone 5D7.1
clone 5D7.1, from mouse
别名:
Retinal-specific ATP-binding cassette transporter, ATP-binding cassette sub-family A member 4, RIM ABC transporter, RIM protein, RmP, Stargardt disease protein
产品名称
Anti-ABCA4 Antibody, clone 5D7.1, clone 5D7.1, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
5D7.1, monoclonal
species reactivity
human
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ABCA4(24)
Immunogen
Recombinant protein corresponding to human ABCA4.
Other Notes
Concentration: Please refer to lot specific datasheet.
Physical form
Format: Purified
Application
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected ABCA4 in human retina tissue.
Anti-ABCA4 Antibody, clone 5D7.1 | MABN287 is an antibody against ABCA4 Antibody for use in Western Blotting, Immunohistochemistry (Paraffin).
General description
Retinal-specific ATP-binding cassette transporter encoded by the gene ABCA4 plays a critical role in the transport of retinoid substrates from the extracellular or intradiscal rod cell membranes to the cytoplasmic membrane surface for processing ultimately into vitamin A and then transferred to the retinal pigment epithelium where it is converted to 11-cis-retinal that active component needed for vision. ABCA4 is localized to the outer segments of rods and cones with a million copies per photoreceptor. ABCA4 is retinal specific protein. Mutations in ABCA4 are linked to several eye-related genetic diseases, such as forms of macular degeneration called Stargardt disease and ARMD2, as well as Retinitis pigmentosa 19, and Cone-rod dystrophy 3.
~275 kDa observed
Analysis Note
Evaluated by Western Blotting in Y79 cell lysate.
Western Blotting Analysis: 5.0 µg/mL of this antibody detected ABCA4 in 200 µg of Y79 cell lysate.
Western Blotting Analysis: 5.0 µg/mL of this antibody detected ABCA4 in 200 µg of Y79 cell lysate.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
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