Anti-Huntingtin Disease (HD/HTT) Antibody

HD exon-1 67Q aggregate.

Clone MW8 is a mouse monoclonal antibody that detects Huntingtin protein. It targets an epitope within nine amino acids in the exon-1 region.

Immunocytochemistry Analysis: A representative lot detected HTT in Immunocytochemistry applications (Legleiter, J., et. al. (2009). J Biol Chem. 284(32):21647-58).

Immunohistochemistry Analysis: A representative lot detected HTT in Immunohistochemistry applications (Ko, J., et. al. (2001). Brain Res Bull. 56(3-4):319-29).

Western Blotting Analysis: A representative lot detected HTT in Western Blotting applications (Legleiter, J., et. al. (2009). J Biol Chem. 284(32):21647-58).

Enzyme Immunoassay (ELISA) Analysis: A representative lot detected HTT in ELISA applications (Ko, J., et. al. (2001). Brain Res Bull. 56(3-4):319-29).

Immunoprecipitation Analysis: A representative lot immunoprecipitated HTT in Immunoprecipitation applications (Baldo, B., et. al. (2012). Chem Biol. 19(2):264-75).

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected HTT in Tissue lysate of 9 month-old WT or Q140 KI HD mice.

Isotype testing: Identity Confirmation by Isotyping Test.

Isotyping Analysis: The identity of this monoclonal antibody is confirmed by isotyping test to be mouse IgG2a.

347.6 kDa calclulated

Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Human, Mouse.

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