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Merck
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主要文件

MABN18

Sigma-Aldrich

Anti-PINK1 Antibody, clone N4/49

clone N4/49, from mouse

别名:

PTEN induced putative kinase 1, protein kinase BRPK, serine/threonine-protein kinase PINK1, PTEN-induced putative kinase protein 1, Parkinson disease (autosomal recessive) 6

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

N4/49, monoclonal

种属反应性

human

技术

immunohistochemistry: suitable
western blot: suitable

同位素/亚型

IgG1κ

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... PINK1(65018)

一般描述

Mutations in the PTEN-induced kinase 1 (PINK1) gene located within the PARK6 locus on chromosome 1p35-p36 have recently been identified in patients with recessive early-onset Parkinson disease. Data suggests that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance.

特异性

This antibody recognizes PINK1.

应用

This Anti-PINK1 Antibody, clone N4/49 is validated for use in IH, WB for the detection of PINK1.
Western Blot Analysis: A previous lot of MABN18 recognized PINK1 in HEK cells and a rat brain LSP, as reported by an independent laboratory (UC Davis/NIH NeuroMab Facility; www.neuromab.org/neuromab@ucdavis.edu).

质量

Evaluated by Immunohistochemistry in human normal brain tissue.

Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected PINK1 in human normal brain tissue.

目标描述

63 kDa Observed

外形

Format: Purified

分析说明

Control
Human normal brain tissue

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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