推荐产品
生物来源
rat
质量水平
偶联物
FITC conjugate
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
1A8, monoclonal
种属反应性
mouse
包装
antibody small pack of 25 μg
浓度
0.5 mg/mL
技术
flow cytometry: suitable
同位素/亚型
IgG2aκ
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
mouse ... Ly6G(546644)
相关类别
一般描述
The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C.
This rat monoclonal antibody Anti-Ly-6G (mouse), FITC & clone 1A8 validated for use in Flow Cytometry for the detection of Ly-6G.
质量
The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Flow Cytometry Analysis: 0.25 µg of this antibody detected Ly-6G in one million C57Bl/6 bone marrow cells.
Flow Cytometry Analysis: 0.25 µg of this antibody detected Ly-6G in one million C57Bl/6 bone marrow cells.
WGK
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