biological source
rat
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
M5/114, monoclonal
species reactivity
mouse
technique(s)
flow cytometry: suitable, immunohistochemistry: suitable, western blot: suitable
isotype
IgG2bκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Cd74(16149)
General description
MHC II类相关不变量链(I-A/I-E),也称Ia抗原相关不变量链,是含有单个甲状腺球蛋白I型结构域的单通道II型膜糖蛋白。它们是MHC II类抗原处理过程中的关键组成部分,在α / β异二聚体合成后形成稳定复合物,并协调复合物从发生II类肽装载的ER区转移。
观测值〜32 kDa。
选择性剪接产生2种亚型:32 kDa(长亚型)和 24 kDa(短亚型)。
选择性剪接产生2种亚型:32 kDa(长亚型)和 24 kDa(短亚型)。
Application
使用经验证可用于WB、FC、IH的该抗-MHC II类(I-A/I-E)抗体,克隆M5/114检测MHC II类(I-A/I-E)。
流式细胞分析:先前批次已被独立实验室用于脾细胞FC。(Bhattacharya, A., et al. (1981). The Journal of immunology.127(6):2488-2496。)
免疫组织化学分析:先前批次已被独立实验室用于胸腺组织IH。(de Bont, E., et al. (1999). Int. Immunol. 11(8):1295-1306.)
免疫组织化学分析:先前批次已被独立实验室用于胸腺组织IH。(de Bont, E., et al. (1999). Int. Immunol. 11(8):1295-1306.)
Physical form
形式:纯化
Analysis Note
已通过蛋白质印迹在小鼠脾组织裂解液中进行了评估。
蛋白质印迹分析:1 µg/mL该抗体在10 µg小鼠脾组织裂解液中检测到MHC II类(I-A/I-E)。
蛋白质印迹分析:1 µg/mL该抗体在10 µg小鼠脾组织裂解液中检测到MHC II类(I-A/I-E)。
Other Notes
浓度:请参考批次特异性浓缩物的检验报告。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MABF33 | 04053252413872 |