跳转至内容
Merck
CN

MABF33

抗-MHC II类(I-A/I-E)抗体,克隆M5/114

clone M5/114, from rat

别名:

CD74 molecule, major histocompatibility complex, class II invariant chain, Ia-associated invariant chain, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), gamma chain of class II antigens, Ia antigen-

登录 查看组织和合同定价。

选择尺寸


关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

抗-MHC II类(I-A/I-E)抗体,克隆M5/114, clone M5/114, from rat

biological source

rat

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

M5/114, monoclonal

species reactivity

mouse

technique(s)

flow cytometry: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG2bκ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

mouse ... Cd74(16149)

Analysis Note

已通过蛋白质印迹在小鼠脾组织裂解液中进行了评估。

蛋白质印迹分析:1 µg/mL该抗体在10 µg小鼠脾组织裂解液中检测到MHC II类(I-A/I-E)。

Application

使用经验证可用于WB、FC、IH的该抗-MHC II类(I-A/I-E)抗体,克隆M5/114检测MHC II类(I-A/I-E)。
流式细胞分析:先前批次已被独立实验室用于脾细胞FC。(Bhattacharya, A., et al. (1981). The Journal of immunology.127(6):2488-2496。)

免疫组织化学分析:先前批次已被独立实验室用于胸腺组织IH。(de Bont, E., et al. (1999). Int. Immunol. 11(8):1295-1306.)

General description

MHC II类相关不变量链(I-A/I-E),也称Ia抗原相关不变量链,是含有单个甲状腺球蛋白I型结构域的单通道II型膜糖蛋白。它们是MHC II类抗原处理过程中的关键组成部分,在α / β异二聚体合成后形成稳定复合物,并协调复合物从发生II类肽装载的ER区转移。
观测值〜32 kDa。
选择性剪接产生2种亚型:32 kDa(长亚型)和 24 kDa(短亚型)。

Other Notes

浓度:请参考批次特异性浓缩物的检验报告。

Physical form

形式:纯化

未找到合适的产品?  

试试我们的产品选型工具.

存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Libin Abraham et al.
Scientific reports, 7(1), 11379-11379 (2017-09-14)
Single-particle tracking (SPT) is a powerful method for exploring single-molecule dynamics in living cells with nanoscale spatiotemporal resolution. Photostability and bright fluorescence make quantum dots (Qdots) a popular choice for SPT. However, their large size could potentially alter the mobility
Serena Y S Tan et al.
Development (Cambridge, England), 143(8), 1318-1327 (2016-03-10)
Macrophages are specialized phagocytic cells, present in all tissues, which engulf and digest pathogens, infected and dying cells, and debris, and can recruit and regulate other immune cells and the inflammatory response and aid in tissue repair. Macrophage subpopulations play
Circulating Porphyromonas gingivalis lipopolysaccharide resets cardiac homeostasis in mice through a matrix metalloproteinase-9-dependent mechanism.
Deleon-Pennell, KY; de Castro Bras, LE; Lindsey, ML
Physiological Reports null
Mahmoud Elashiry et al.
Journal of extracellular vesicles, 9(1), 1795362-1795362 (2020-09-19)
Chronic bone degenerative diseases represent a major threat to the health and well-being of the population, particularly those with advanced age. This study isolated exosomes (EXO), natural nano-particles, from dendritic cells, the "directors" of the immune response, to examine the
Madison Bolger-Munro et al.
eLife, 8 (2019-06-04)
When B cells encounter antigens on the surface of an antigen-presenting cell (APC), B cell receptors (BCRs) are gathered into microclusters that recruit signaling enzymes. These microclusters then move centripetally and coalesce into the central supramolecular activation cluster of an

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持